Q-lipid-containing membranes show high in-plane conductivity using a membrane-on-a-chip setup
Summary: The light-driven reactions of photosynthesis as well as the mitochondrial power supply are located in specialized membranes containing a high fraction of redox-active lipids. In-plane charge transfer along such cell membranes is currently thought to be facilitated by the diffusion of redox...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-02-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004222021915 |
| _version_ | 1797903381312831488 |
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| author | Ulrich Ramach Jakob Andersson Rosmarie Schöfbeck Markus Valtiner |
| author_facet | Ulrich Ramach Jakob Andersson Rosmarie Schöfbeck Markus Valtiner |
| author_sort | Ulrich Ramach |
| collection | DOAJ |
| description | Summary: The light-driven reactions of photosynthesis as well as the mitochondrial power supply are located in specialized membranes containing a high fraction of redox-active lipids. In-plane charge transfer along such cell membranes is currently thought to be facilitated by the diffusion of redox lipids and proteins. Using a membrane on-a-chip setup, we show here that redox-active model membranes can sustain surprisingly high currents (mA) in-plane at distances of 25 μm. We also show the same phenomenon in free-standing monolayers at the air-water interface once the film is compressed such that the distance between redox centers is below 1 nm. Our data suggest that charge transfer within cell walls hosting electron transfer chains could be enabled by the coupling of redox-lipids via simultaneous electron and proton in-plane hopping, similar to conductive polymers. This has major implications for our understanding of the role of lipid membranes, suggesting that Q-lipid-containing membranes may be essential for evolving the complex redox machineries of life. |
| first_indexed | 2024-04-10T09:32:00Z |
| format | Article |
| id | doaj.art-6d9a186384cb454b96e350d4a4e69432 |
| institution | Directory Open Access Journal |
| issn | 2589-0042 |
| language | English |
| last_indexed | 2024-04-10T09:32:00Z |
| publishDate | 2023-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj.art-6d9a186384cb454b96e350d4a4e694322023-02-19T04:26:32ZengElsevieriScience2589-00422023-02-01262105918Q-lipid-containing membranes show high in-plane conductivity using a membrane-on-a-chip setupUlrich Ramach0Jakob Andersson1Rosmarie Schöfbeck2Markus Valtiner3Institute for Applied Physics, Vienna University of Technology, 1090 Vienna, Austria; Competence Center for Electrochemical, Surface Technologies, CEST, 2700 Wiener Neustadt, AustriaInstitute for Applied Physics, Vienna University of Technology, 1090 Vienna, Austria; Biosensor Technologies, Austrian Institute of Technology, 1210 Vienna, Austria; Corresponding authorInstitute for Applied Physics, Vienna University of Technology, 1090 Vienna, AustriaInstitute for Applied Physics, Vienna University of Technology, 1090 Vienna, Austria; Competence Center for Electrochemical, Surface Technologies, CEST, 2700 Wiener Neustadt, Austria; Corresponding authorSummary: The light-driven reactions of photosynthesis as well as the mitochondrial power supply are located in specialized membranes containing a high fraction of redox-active lipids. In-plane charge transfer along such cell membranes is currently thought to be facilitated by the diffusion of redox lipids and proteins. Using a membrane on-a-chip setup, we show here that redox-active model membranes can sustain surprisingly high currents (mA) in-plane at distances of 25 μm. We also show the same phenomenon in free-standing monolayers at the air-water interface once the film is compressed such that the distance between redox centers is below 1 nm. Our data suggest that charge transfer within cell walls hosting electron transfer chains could be enabled by the coupling of redox-lipids via simultaneous electron and proton in-plane hopping, similar to conductive polymers. This has major implications for our understanding of the role of lipid membranes, suggesting that Q-lipid-containing membranes may be essential for evolving the complex redox machineries of life.http://www.sciencedirect.com/science/article/pii/S2589004222021915sensorlipidmembrane architectureNanotechnologyBioelectronics |
| spellingShingle | Ulrich Ramach Jakob Andersson Rosmarie Schöfbeck Markus Valtiner Q-lipid-containing membranes show high in-plane conductivity using a membrane-on-a-chip setup iScience sensor lipid membrane architecture Nanotechnology Bioelectronics |
| title | Q-lipid-containing membranes show high in-plane conductivity using a membrane-on-a-chip setup |
| title_full | Q-lipid-containing membranes show high in-plane conductivity using a membrane-on-a-chip setup |
| title_fullStr | Q-lipid-containing membranes show high in-plane conductivity using a membrane-on-a-chip setup |
| title_full_unstemmed | Q-lipid-containing membranes show high in-plane conductivity using a membrane-on-a-chip setup |
| title_short | Q-lipid-containing membranes show high in-plane conductivity using a membrane-on-a-chip setup |
| title_sort | q lipid containing membranes show high in plane conductivity using a membrane on a chip setup |
| topic | sensor lipid membrane architecture Nanotechnology Bioelectronics |
| url | http://www.sciencedirect.com/science/article/pii/S2589004222021915 |
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