SARS-CoV-2 Omicron Spike shows strong binding affinity and favourable interaction landscape with the TLR4/MD2 compared to other variants

Emergences of SARS-CoV-2 variants have made the pandemic more critical. Toll-like receptor 4 (TLR4) recognizes the molecular patterns of pathogens and activates the production of proinflammatory cytokines to restrain the infection. We have identified a molecular basis of interaction between the Spik...

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Hlavní autoři: Chiranjib Chakraborty, Bidyut Mallick, Manojit Bhattacharya, Siddappa N. Byrareddy
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2024-03-01
Edice:Journal of Genetic Engineering and Biotechnology
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S1687157X23015184