Germline defects of familial hemophagocytic lymphohistiocytosis-related genes presenting as adult-onset peripheral T-cell lymphoma
Germline mutations in genes involved in perforin-granzyme-mediated cytotoxicity such as PRF1, UNC13D, STX11, and STXBP2 were known to cause familial hemophagocytic lymphohistiocytosis (FHL). In this study, we reported a unique group of 3 patients with germline mutations of UNC13D and STX11 genes and...
Main Authors: | Chong Wei, Danqing Zhao, Song Xue, Hao Cai, Congwei Jia, Daobin Zhou, Wei Zhang |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2024-02-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2024.1365975/full |
Similar Items
-
Secondary hemophagocytic lymphohistiocytosis triggered by peripheral T‐cell lymphoma: An unusual case report
by: Yuxuan Che, et al.
Published: (2022-11-01) -
A Decade of Lymphoma-Associated Hemophagocytic Lymphohistiocytosis: Does the Outcome Improve?
by: Cheng-Hsien Lin, et al.
Published: (2021-10-01) -
Approaching hemophagocytic lymphohistiocytosis
by: Aurora Chinnici, et al.
Published: (2023-06-01) -
A case of primary cutaneous γδT cell lymphoma complicated with hemophagocytic lymphohistiocytosis
by: Junchi TANG, et al.
Published: (2023-02-01) -
Erratum: Approaching hemophagocytic lymphohistiocytosis
by: Frontiers Production Office
Published: (2024-01-01)