Patients preferences for different corticosteroid vehicles are highly variable
Introduction: Topical corticosteroids, available in an array of vehicles are used to control a variety of inflammatory skin diseases. Patients preferences for different vehicles may affect their willingness to use treatment. We assess corticosteroid vehicle preference and potential impact of topical...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2020-02-01
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| Series: | Journal of Dermatological Treatment |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09546634.2018.1473837 |
| _version_ | 1797683742889738240 |
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| author | Kayla Felix Emily Unrue Meyene Inyang Leah A. Cardwell Elias Oussedik Irma Richardson Steven R. Feldman |
| author_facet | Kayla Felix Emily Unrue Meyene Inyang Leah A. Cardwell Elias Oussedik Irma Richardson Steven R. Feldman |
| author_sort | Kayla Felix |
| collection | DOAJ |
| description | Introduction: Topical corticosteroids, available in an array of vehicles are used to control a variety of inflammatory skin diseases. Patients preferences for different vehicles may affect their willingness to use treatment. We assess corticosteroid vehicle preference and potential impact of topical characteristics on adherence and quality of life in patients with psoriasis. Methods: Subjects with psoriasis were recruited from Wake Forest University Dermatology Clinic. Subjects sampled desoximetasone 0.25% spray, betamethasone valerate 0.1% cream, triamcinolone acetonide 0.1% ointment, fluocinonide 0.05% gel, betamethasone valerate 0.1% lotion, clobetasol propionate 0.05% foam, and fluocinonide 0.05% solution in a predetermined randomized order. Subjects completed a Vehicle Preference Measure, Determinants of Adherence Measure, and a Determinants of Quality of Life Measure. Results: Patients preferences for the various products were highly variable. Regarding Determinants of Adherence, patients perception of absorption of the medication was ranked as ‘quite important/extremely important’ by 85% of total subjects. A majority of patients rated medication side effects as ‘quite important/extremely important’ when asked to consider topical characteristics effect on quality of life. Discussion: There was wide variation in patient preference for topical medication vehicles used for treating psoriasis. Several vehicle characteristics were considered important to adherence. Given the marked variation in vehicle preference, topical treatment should be individualized according to patients preferences. |
| first_indexed | 2024-03-12T00:19:11Z |
| format | Article |
| id | doaj.art-6da4d06b60b34c64a82dacd933bd314b |
| institution | Directory Open Access Journal |
| issn | 0954-6634 1471-1753 |
| language | English |
| last_indexed | 2024-03-12T00:19:11Z |
| publishDate | 2020-02-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj.art-6da4d06b60b34c64a82dacd933bd314b2023-09-15T14:08:32ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532020-02-0131214715110.1080/09546634.2018.14738371473837Patients preferences for different corticosteroid vehicles are highly variableKayla Felix0Emily Unrue1Meyene Inyang2Leah A. Cardwell3Elias Oussedik4Irma Richardson5Steven R. Feldman6Center for Dermatology ResearchCenter for Dermatology ResearchCenter for Dermatology ResearchCenter for Dermatology ResearchCenter for Dermatology ResearchCenter for Dermatology ResearchCenter for Dermatology ResearchIntroduction: Topical corticosteroids, available in an array of vehicles are used to control a variety of inflammatory skin diseases. Patients preferences for different vehicles may affect their willingness to use treatment. We assess corticosteroid vehicle preference and potential impact of topical characteristics on adherence and quality of life in patients with psoriasis. Methods: Subjects with psoriasis were recruited from Wake Forest University Dermatology Clinic. Subjects sampled desoximetasone 0.25% spray, betamethasone valerate 0.1% cream, triamcinolone acetonide 0.1% ointment, fluocinonide 0.05% gel, betamethasone valerate 0.1% lotion, clobetasol propionate 0.05% foam, and fluocinonide 0.05% solution in a predetermined randomized order. Subjects completed a Vehicle Preference Measure, Determinants of Adherence Measure, and a Determinants of Quality of Life Measure. Results: Patients preferences for the various products were highly variable. Regarding Determinants of Adherence, patients perception of absorption of the medication was ranked as ‘quite important/extremely important’ by 85% of total subjects. A majority of patients rated medication side effects as ‘quite important/extremely important’ when asked to consider topical characteristics effect on quality of life. Discussion: There was wide variation in patient preference for topical medication vehicles used for treating psoriasis. Several vehicle characteristics were considered important to adherence. Given the marked variation in vehicle preference, topical treatment should be individualized according to patients preferences.http://dx.doi.org/10.1080/09546634.2018.1473837desoximetasone 0.025 spraytopical medicationcorticosteroids |
| spellingShingle | Kayla Felix Emily Unrue Meyene Inyang Leah A. Cardwell Elias Oussedik Irma Richardson Steven R. Feldman Patients preferences for different corticosteroid vehicles are highly variable Journal of Dermatological Treatment desoximetasone 0.025 spray topical medication corticosteroids |
| title | Patients preferences for different corticosteroid vehicles are highly variable |
| title_full | Patients preferences for different corticosteroid vehicles are highly variable |
| title_fullStr | Patients preferences for different corticosteroid vehicles are highly variable |
| title_full_unstemmed | Patients preferences for different corticosteroid vehicles are highly variable |
| title_short | Patients preferences for different corticosteroid vehicles are highly variable |
| title_sort | patients preferences for different corticosteroid vehicles are highly variable |
| topic | desoximetasone 0.025 spray topical medication corticosteroids |
| url | http://dx.doi.org/10.1080/09546634.2018.1473837 |
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