SRC kinase-mediated signaling pathways and targeted therapies in breast cancer

SRC kinase-mediated signaling pathways and targeted therapies in breast cancer

Abstract Breast cancer (BC) has been ranked the most common malignant tumor throughout the world and is also a leading cause of cancer-related deaths among women. SRC family kinases (SFKs) belong to the non-receptor tyrosine kinase (nRTK) family, which has eleven members sharing similar structure an...

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Bibliographic Details
Main Authors: Juan Luo, Hailin Zou, Yibo Guo, Tongyu Tong, Liping Ye, Chengming Zhu, Liang Deng, Bo Wang, Yihang Pan, Peng Li
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Breast Cancer Research
Subjects:
Breast cancer
SRC kinase
Signaling transduction
Tyrosine phosphorylation
Targeted therapy
Online Access:https://doi.org/10.1186/s13058-022-01596-y

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