Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis
A genome-wide association study identifies MFGE8 as protective against coronary atherosclerosis in European and East Asian populations.
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-08-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03552-0 |
| _version_ | 1828322360317444096 |
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| author | Sanni E. Ruotsalainen Ida Surakka Nina Mars Juha Karjalainen Mitja Kurki Masahiro Kanai Kristi Krebs Sarah Graham Pashupati P. Mishra Binisha H. Mishra Juha Sinisalo Priit Palta Terho Lehtimäki Olli Raitakari Estonian Biobank Research Team Lili Milani The Biobank Japan Project Yukinori Okada FinnGen Aarno Palotie Elisabeth Widen Mark J. Daly Samuli Ripatti |
| author_facet | Sanni E. Ruotsalainen Ida Surakka Nina Mars Juha Karjalainen Mitja Kurki Masahiro Kanai Kristi Krebs Sarah Graham Pashupati P. Mishra Binisha H. Mishra Juha Sinisalo Priit Palta Terho Lehtimäki Olli Raitakari Estonian Biobank Research Team Lili Milani The Biobank Japan Project Yukinori Okada FinnGen Aarno Palotie Elisabeth Widen Mark J. Daly Samuli Ripatti |
| author_sort | Sanni E. Ruotsalainen |
| collection | DOAJ |
| description | A genome-wide association study identifies MFGE8 as protective against coronary atherosclerosis in European and East Asian populations. |
| first_indexed | 2024-04-13T18:39:48Z |
| format | Article |
| id | doaj.art-6dacc6359dd146e9bd207b6e44a8c3fb |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-13T18:39:48Z |
| publishDate | 2022-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-6dacc6359dd146e9bd207b6e44a8c3fb2022-12-22T02:34:46ZengNature PortfolioCommunications Biology2399-36422022-08-015111610.1038/s42003-022-03552-0Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosisSanni E. Ruotsalainen0Ida Surakka1Nina Mars2Juha Karjalainen3Mitja Kurki4Masahiro Kanai5Kristi Krebs6Sarah Graham7Pashupati P. Mishra8Binisha H. Mishra9Juha Sinisalo10Priit Palta11Terho Lehtimäki12Olli Raitakari13Estonian Biobank Research TeamLili Milani14The Biobank Japan ProjectYukinori Okada15FinnGenAarno Palotie16Elisabeth Widen17Mark J. Daly18Samuli Ripatti19Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of HelsinkiDepartment of Internal Medicine, University of MichiganInstitute for Molecular Medicine Finland (FIMM), HiLIFE, University of HelsinkiThe Broad Institute of MIT and HarvardThe Broad Institute of MIT and HarvardThe Broad Institute of MIT and HarvardEstonian Genome Centre, Institute of Genomics, University of TartuDepartment of Internal Medicine, University of MichiganDepartment of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere UniversityDepartment of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere UniversityHeart and Lung Center, Helsinki University Hospital and Helsinki UniversityInstitute for Molecular Medicine Finland (FIMM), HiLIFE, University of HelsinkiDepartment of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere UniversityResearch Centre of Applied and Preventive Cardiovascular Medicine, University of TurkuEstonian Genome Centre, Institute of Genomics, University of TartuDepartment of Statistical Genetics, Osaka University Graduate School of MedicineInstitute for Molecular Medicine Finland (FIMM), HiLIFE, University of HelsinkiInstitute for Molecular Medicine Finland (FIMM), HiLIFE, University of HelsinkiInstitute for Molecular Medicine Finland (FIMM), HiLIFE, University of HelsinkiInstitute for Molecular Medicine Finland (FIMM), HiLIFE, University of HelsinkiA genome-wide association study identifies MFGE8 as protective against coronary atherosclerosis in European and East Asian populations.https://doi.org/10.1038/s42003-022-03552-0 |
| spellingShingle | Sanni E. Ruotsalainen Ida Surakka Nina Mars Juha Karjalainen Mitja Kurki Masahiro Kanai Kristi Krebs Sarah Graham Pashupati P. Mishra Binisha H. Mishra Juha Sinisalo Priit Palta Terho Lehtimäki Olli Raitakari Estonian Biobank Research Team Lili Milani The Biobank Japan Project Yukinori Okada FinnGen Aarno Palotie Elisabeth Widen Mark J. Daly Samuli Ripatti Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis Communications Biology |
| title | Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis |
| title_full | Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis |
| title_fullStr | Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis |
| title_full_unstemmed | Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis |
| title_short | Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis |
| title_sort | inframe insertion and splice site variants in mfge8 associate with protection against coronary atherosclerosis |
| url | https://doi.org/10.1038/s42003-022-03552-0 |
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