Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions
One of the useful function of melatonin is its protective effect against endogenous oxidants. The object of this investigation was to study the protective effect of melatonin on stress-induced gastric lesions."nResults: Our results show that pretreatment of animals with melatonin decrease t...
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Format: | Article |
Language: | fas |
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Tehran University of Medical Sciences
2003-08-01
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Series: | Tehran University Medical Journal |
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Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5439.pdf&manuscript_id=5439 |
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author | M. Samini AR. Dehpour E. Babazadeh Khamneh |
author_facet | M. Samini AR. Dehpour E. Babazadeh Khamneh |
author_sort | M. Samini |
collection | DOAJ |
description | One of the useful function of melatonin is its protective effect against endogenous oxidants. The object of this investigation was to study the protective effect of melatonin on stress-induced gastric lesions."nResults: Our results show that pretreatment of animals with melatonin decrease the stress-induced gastric lesions dose dependently."nL-NAME, a nitric oxide synthesis inhibitor, potentiat the stress-induce gastric lesions and melatonin produced gastro-protective effect against concurrent stress and L-NAME-induced gastric lesions."nConclusion: Our results indicate that melatonin may produce its gastro-protective effect Via increasing level of nitric oxide. |
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format | Article |
id | doaj.art-6dad6e3d35d14ddaacef2b4ca6a2998b |
institution | Directory Open Access Journal |
issn | 1683-1764 1735-7322 |
language | fas |
last_indexed | 2024-12-24T04:14:15Z |
publishDate | 2003-08-01 |
publisher | Tehran University of Medical Sciences |
record_format | Article |
series | Tehran University Medical Journal |
spelling | doaj.art-6dad6e3d35d14ddaacef2b4ca6a2998b2022-12-21T17:15:59ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222003-08-01613178181Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric LesionsM. SaminiAR. Dehpour E. Babazadeh KhamnehOne of the useful function of melatonin is its protective effect against endogenous oxidants. The object of this investigation was to study the protective effect of melatonin on stress-induced gastric lesions."nResults: Our results show that pretreatment of animals with melatonin decrease the stress-induced gastric lesions dose dependently."nL-NAME, a nitric oxide synthesis inhibitor, potentiat the stress-induce gastric lesions and melatonin produced gastro-protective effect against concurrent stress and L-NAME-induced gastric lesions."nConclusion: Our results indicate that melatonin may produce its gastro-protective effect Via increasing level of nitric oxide.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5439.pdf&manuscript_id=5439peptic lesions |
spellingShingle | M. Samini AR. Dehpour E. Babazadeh Khamneh Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions Tehran University Medical Journal peptic lesions |
title | Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions |
title_full | Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions |
title_fullStr | Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions |
title_full_unstemmed | Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions |
title_short | Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions |
title_sort | study of the effect of melatonin on water immersion stress induced gastric lesions |
topic | peptic lesions |
url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5439.pdf&manuscript_id=5439 |
work_keys_str_mv | AT msamini studyoftheeffectofmelatoninonwaterimmersionstressinducedgastriclesions AT ardehpourebabazadehkhamneh studyoftheeffectofmelatoninonwaterimmersionstressinducedgastriclesions |