Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions

One of the useful function of melatonin is its protective effect against endogenous oxidants. The object of this investigation was to study the protective effect of melatonin on stress-induced gastric lesions."nResults: Our results show that pretreatment of animals with melatonin decrease t...

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Main Authors: M. Samini, AR. Dehpour E. Babazadeh Khamneh
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2003-08-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5439.pdf&manuscript_id=5439
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author M. Samini
AR. Dehpour E. Babazadeh Khamneh
author_facet M. Samini
AR. Dehpour E. Babazadeh Khamneh
author_sort M. Samini
collection DOAJ
description One of the useful function of melatonin is its protective effect against endogenous oxidants. The object of this investigation was to study the protective effect of melatonin on stress-induced gastric lesions."nResults: Our results show that pretreatment of animals with melatonin decrease the stress-induced gastric lesions dose dependently."nL-NAME, a nitric oxide synthesis inhibitor, potentiat the stress-induce gastric lesions and melatonin produced gastro-protective effect against concurrent stress and L-NAME-induced gastric lesions."nConclusion: Our results indicate that melatonin may produce its gastro-protective effect Via increasing level of nitric oxide.
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spelling doaj.art-6dad6e3d35d14ddaacef2b4ca6a2998b2022-12-21T17:15:59ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222003-08-01613178181Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric LesionsM. SaminiAR. Dehpour E. Babazadeh KhamnehOne of the useful function of melatonin is its protective effect against endogenous oxidants. The object of this investigation was to study the protective effect of melatonin on stress-induced gastric lesions."nResults: Our results show that pretreatment of animals with melatonin decrease the stress-induced gastric lesions dose dependently."nL-NAME, a nitric oxide synthesis inhibitor, potentiat the stress-induce gastric lesions and melatonin produced gastro-protective effect against concurrent stress and L-NAME-induced gastric lesions."nConclusion: Our results indicate that melatonin may produce its gastro-protective effect Via increasing level of nitric oxide.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5439.pdf&manuscript_id=5439peptic lesions
spellingShingle M. Samini
AR. Dehpour E. Babazadeh Khamneh
Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions
Tehran University Medical Journal
peptic lesions
title Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions
title_full Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions
title_fullStr Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions
title_full_unstemmed Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions
title_short Study Of The Effect Of Melatonin On Water Immersion Stress-Induced Gastric Lesions
title_sort study of the effect of melatonin on water immersion stress induced gastric lesions
topic peptic lesions
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5439.pdf&manuscript_id=5439
work_keys_str_mv AT msamini studyoftheeffectofmelatoninonwaterimmersionstressinducedgastriclesions
AT ardehpourebabazadehkhamneh studyoftheeffectofmelatoninonwaterimmersionstressinducedgastriclesions