Glucose transporter 3 (GLUT3) promotes lactylation modifications by regulating lactate dehydrogenase A (LDHA) in gastric cancer

Glucose transporter 3 (GLUT3) promotes lactylation modifications by regulating lactate dehydrogenase A (LDHA) in gastric cancer

Abstract Objectives Glucose transporter 3 (GLUT3) plays a major role in glycolysis and glucose metabolism in cancer cells. We aimed to investigate the correlation between GLUT3 and histone lactylation modification in the occurrence and progression of gastric cancer. Materials and methods We initiall...

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Bibliographic Details
Main Authors: Hao Yang, Shifeng Yang, Jixing He, Wenqiang Li, Ange Zhang, Nana Li, Guangkai Zhou, Boshi Sun
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cancer Cell International
Subjects:
Glucose transporter 3
Lactylation
Lactate dehydrogenase A
Epithelial-mesenchymal transition
Gastric cancer
Online Access:https://doi.org/10.1186/s12935-023-03162-8

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