Risk Stratification of Endoscopic Submucosal Dissection in Colon Tumors
Background: Endoscopic submucosal dissection (ESD) is a technique proven effective in the treatment of early neoplastic lesions in the gastrointestinal tract. However, in the case of colon lesions, many doubts remain. The purpose of our study is to stratify the success rates of the ESD procedure in...
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| Format: | Article |
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MDPI AG
2022-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/6/1560 |
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| author | Katarzyna Winter Marcin Włodarczyk Jakub Włodarczyk Igor Dąbrowski Ewa Małecka-Wojciesko Adam Dziki Michał Spychalski |
| author_facet | Katarzyna Winter Marcin Włodarczyk Jakub Włodarczyk Igor Dąbrowski Ewa Małecka-Wojciesko Adam Dziki Michał Spychalski |
| author_sort | Katarzyna Winter |
| collection | DOAJ |
| description | Background: Endoscopic submucosal dissection (ESD) is a technique proven effective in the treatment of early neoplastic lesions in the gastrointestinal tract. However, in the case of colon lesions, many doubts remain. The purpose of our study is to stratify the success rates of the ESD procedure in the colon. Materials and Methods: A retrospective analysis of 601 patients who underwent ESD procedure for colorectal neoplasm from 2016 to 2019 in Center of Bowel Treatment, Brzeziny, Poland. Excluding 335 rectal neoplasms, we selected 266 patients with lesions located in the colon. Results: Lesions located in the left colon were characterized by the statistically higher en bloc resection and success rate, compared with the right colon—87.76% vs. 73.95% (<i>p</i> = 0.004) and 83.67% vs. 69.75% (<i>p</i> = 0.007), respectively. The success rate was significantly lower in lesions with submucosal cancer, compared to low- and high-grade dysplasia (<i>p</i> < 0.001). Polyps located in the right colon were characterized by a slightly higher complication rate compared to the left colon, without statistical significance—13.45% vs. 9.52% (<i>p</i> = 0.315). Conclusions: Our results show that colonic ESD has a high success rate, especially in the left colon, with a low risk of complications, slightly higher than in the right colon. |
| first_indexed | 2024-03-09T19:37:33Z |
| format | Article |
| id | doaj.art-6db1083cf06744279d2d22ec8ea09f86 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T19:37:33Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-6db1083cf06744279d2d22ec8ea09f862023-11-24T01:48:18ZengMDPI AGJournal of Clinical Medicine2077-03832022-03-01116156010.3390/jcm11061560Risk Stratification of Endoscopic Submucosal Dissection in Colon TumorsKatarzyna Winter0Marcin Włodarczyk1Jakub Włodarczyk2Igor Dąbrowski3Ewa Małecka-Wojciesko4Adam Dziki5Michał Spychalski6Center of Bowel Treatment, 95-060 Brzeziny, PolandDepartment of General and Oncological Surgery, Medical University of Lodz, 90-153 Lodz, PolandDepartment of General and Oncological Surgery, Medical University of Lodz, 90-153 Lodz, PolandCenter of Bowel Treatment, 95-060 Brzeziny, PolandDepartment of Digestive Tract Diseases, Medical University of Lodz, 90-153 Lodz, PolandDepartment of General and Colorectal Surgery, Medical University of Lodz, Haller Square 1, 90-419 Lodz, PolandCenter of Bowel Treatment, 95-060 Brzeziny, PolandBackground: Endoscopic submucosal dissection (ESD) is a technique proven effective in the treatment of early neoplastic lesions in the gastrointestinal tract. However, in the case of colon lesions, many doubts remain. The purpose of our study is to stratify the success rates of the ESD procedure in the colon. Materials and Methods: A retrospective analysis of 601 patients who underwent ESD procedure for colorectal neoplasm from 2016 to 2019 in Center of Bowel Treatment, Brzeziny, Poland. Excluding 335 rectal neoplasms, we selected 266 patients with lesions located in the colon. Results: Lesions located in the left colon were characterized by the statistically higher en bloc resection and success rate, compared with the right colon—87.76% vs. 73.95% (<i>p</i> = 0.004) and 83.67% vs. 69.75% (<i>p</i> = 0.007), respectively. The success rate was significantly lower in lesions with submucosal cancer, compared to low- and high-grade dysplasia (<i>p</i> < 0.001). Polyps located in the right colon were characterized by a slightly higher complication rate compared to the left colon, without statistical significance—13.45% vs. 9.52% (<i>p</i> = 0.315). Conclusions: Our results show that colonic ESD has a high success rate, especially in the left colon, with a low risk of complications, slightly higher than in the right colon.https://www.mdpi.com/2077-0383/11/6/1560ESDcolon tumorscomplication ratesuccess rate |
| spellingShingle | Katarzyna Winter Marcin Włodarczyk Jakub Włodarczyk Igor Dąbrowski Ewa Małecka-Wojciesko Adam Dziki Michał Spychalski Risk Stratification of Endoscopic Submucosal Dissection in Colon Tumors Journal of Clinical Medicine ESD colon tumors complication rate success rate |
| title | Risk Stratification of Endoscopic Submucosal Dissection in Colon Tumors |
| title_full | Risk Stratification of Endoscopic Submucosal Dissection in Colon Tumors |
| title_fullStr | Risk Stratification of Endoscopic Submucosal Dissection in Colon Tumors |
| title_full_unstemmed | Risk Stratification of Endoscopic Submucosal Dissection in Colon Tumors |
| title_short | Risk Stratification of Endoscopic Submucosal Dissection in Colon Tumors |
| title_sort | risk stratification of endoscopic submucosal dissection in colon tumors |
| topic | ESD colon tumors complication rate success rate |
| url | https://www.mdpi.com/2077-0383/11/6/1560 |
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