Integration of pathologic characteristics, genetic risk and lifestyle exposure for colorectal cancer survival assessment

Integration of pathologic characteristics, genetic risk and lifestyle exposure for colorectal cancer survival assessment

Abstract The development of an effective survival prediction tool is key for reducing colorectal cancer mortality. Here, we apply a three-stage study to devise a polygenic prognostic score (PPS) for stratifying colorectal cancer overall survival. Leveraging two cohorts of 3703 patients, we first per...

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Bibliographic Details
Main Authors: Junyi Xin, Dongying Gu, Shuwei Li, Sangni Qian, Yifei Cheng, Wei Shao, Shuai Ben, Silu Chen, Linjun Zhu, Mingjuan Jin, Kun Chen, Zhibin Hu, Zhengdong Zhang, Mulong Du, Hongbing Shen, Meilin Wang
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47204-9

Internet

https://doi.org/10.1038/s41467-024-47204-9

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