Synthesis and Antitumor Activities of Derivatives of the Marine Mangrove Fungal Metabolite Deoxybostrycin

Synthesis and Antitumor Activities of Derivatives of the Marine Mangrove Fungal Metabolite Deoxybostrycin

Deoxybostrycin (1) is an anthraquinone compound derived from the marine mangrove fungus Nigrospora sp. No. 1403 and has potential to be a lead for new drugs because of its various biological properties. A series of new derivatives (2–22) of deoxybostrycin were synthesized. The in vitro...

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Bibliographic Details
Main Authors: Zhi-Gang She, Yuhua Long, Yong-Cheng Lin, Sheng-Ping Chen, Jue-Heng Wu, Bing Yang, Jia Li, Li-Li Zhong, Hong Chen, Xun Zhu
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Marine Drugs
Subjects:
deoxybostrycin derivatives
antitumor activity
marine mangrove
anthraquinone
Online Access:http://www.mdpi.com/1660-3397/10/12/2715

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