Up-Regulation of LINC00665 Facilitates the Malignant Progression of Prostate Cancer by Epigenetically Silencing KLF2 Through EZH2 and LSD1

Up-Regulation of LINC00665 Facilitates the Malignant Progression of Prostate Cancer by Epigenetically Silencing KLF2 Through EZH2 and LSD1

This study aimed to explore the function of LINC00665 on the proliferation and metastasis of prostate cancer (PCa), and the potential regulatory mechanisms were also investigated. The expression level of LINC00665 in 50 pairs of PCa tissues and adjacent ones was studied by qRT-PCR, and the associati...

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Bibliographic Details
Main Authors: Peng Xue, Miao Yan, Kunpeng Wang, Jinbao Gu, Bing Zhong, Chuanquan Tu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
LINC00665
malignant progression
prostate cancer
KLF2
EZH2
LSD1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.639060/full

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