Serum Zinc in Iraqi Acute Leukemic Patients

Background: Leukemia is a group of malignant disorders associated with increased numbers of blood white blood cells. Acute leukemia occurs at all ages. Because zinc influences many body systems and functions, zinc is an essential nutrient for tissue growth, cellular division, protein synthesis DNA...

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Main Author: Shatha Salah
Format: Article
Language:English
Published: University of Baghdad/ Al-Kindy College of Medicine 2009-06-01
Series:مجله كليه طب الكندي
Subjects:
Online Access:https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/714
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author Shatha Salah
author_facet Shatha Salah
author_sort Shatha Salah
collection DOAJ
description Background: Leukemia is a group of malignant disorders associated with increased numbers of blood white blood cells. Acute leukemia occurs at all ages. Because zinc influences many body systems and functions, zinc is an essential nutrient for tissue growth, cellular division, protein synthesis DNA and RNA replication it also ought to play a critical role in the growth of tumor. In this study, serum zinc was estimated in leukemic patients and compared with healthy subjects. Methods: The subjects in the present study were; fourtyfour depressed patients aged (14-48 year), thirty-one apparently healthy subjects were selected as control group. Their sex and age were comparable to that of patients. Determination of serum zinc was carried out using flame atomic absorption spectrophotometer. Results: The results showed a significant decrease in serum zinc at (p<0.05) in leukemic patients as compared with healthy control. Conclusion: The decrease in serum concentration of zinc in leukemia can be explained by means of the changes in immunity system and the need for zinc to synthesize nucleic acid and tumor cell division in this disorder in addition to other possible mechanisms
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spelling doaj.art-6dc34b09066e4d8f967879069a7142112022-12-22T03:12:00ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652009-06-0151Serum Zinc in Iraqi Acute Leukemic PatientsShatha Salah0e department of Microbiology/Medical Biology, Al-Kindy College of Medicine., Baghdad, Iraq. Background: Leukemia is a group of malignant disorders associated with increased numbers of blood white blood cells. Acute leukemia occurs at all ages. Because zinc influences many body systems and functions, zinc is an essential nutrient for tissue growth, cellular division, protein synthesis DNA and RNA replication it also ought to play a critical role in the growth of tumor. In this study, serum zinc was estimated in leukemic patients and compared with healthy subjects. Methods: The subjects in the present study were; fourtyfour depressed patients aged (14-48 year), thirty-one apparently healthy subjects were selected as control group. Their sex and age were comparable to that of patients. Determination of serum zinc was carried out using flame atomic absorption spectrophotometer. Results: The results showed a significant decrease in serum zinc at (p<0.05) in leukemic patients as compared with healthy control. Conclusion: The decrease in serum concentration of zinc in leukemia can be explained by means of the changes in immunity system and the need for zinc to synthesize nucleic acid and tumor cell division in this disorder in addition to other possible mechanisms https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/714leukemia,zinc,inflammation
spellingShingle Shatha Salah
Serum Zinc in Iraqi Acute Leukemic Patients
مجله كليه طب الكندي
leukemia,
zinc,
inflammation
title Serum Zinc in Iraqi Acute Leukemic Patients
title_full Serum Zinc in Iraqi Acute Leukemic Patients
title_fullStr Serum Zinc in Iraqi Acute Leukemic Patients
title_full_unstemmed Serum Zinc in Iraqi Acute Leukemic Patients
title_short Serum Zinc in Iraqi Acute Leukemic Patients
title_sort serum zinc in iraqi acute leukemic patients
topic leukemia,
zinc,
inflammation
url https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/714
work_keys_str_mv AT shathasalah serumzinciniraqiacuteleukemicpatients