Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis

Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis

Hematopoietic stem cells produce diverse cell lineages. Here, the authors apply single-cell RNA-seq, computational integration of non-perturbative approaches for fate-mapping, and mitotic tracking to chart lineage decisions in native hematopoiesis and identify megakaryocyte progenitors that directly...

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Bibliographic Details
Main Authors: Mina N. F. Morcos, Congxin Li, Clara M. Munz, Alessandro Greco, Nicole Dressel, Susanne Reinhardt, Katrin Sameith, Andreas Dahl, Nils B. Becker, Axel Roers, Thomas Höfer, Alexander Gerbaulet
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31914-z

Internet

https://doi.org/10.1038/s41467-022-31914-z

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