Hypothyroidism and Ramadan fasting

Introduction: Fasting during the holy month of Ramadan is an obligation for all adult, healthy Muslims. As several studies have indicated, both fasting and energy restriction can alter thyroid hormone metabolism and affect the clinical features and well-being of hypothyroid patients. Hypothyroidism...

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Main Authors: Mousa-Al-Reza Hadjzadeh, Roghayeh Pakdel, Parichehr Hayatdavoudi, Mohsen Nematy
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2014-05-01
Series:Journal of Fasting and Health
Subjects:
Online Access:http://jnfh.mums.ac.ir/article_3254_de0721089637d14a9e73c60a8c09183b.pdf
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author Mousa-Al-Reza Hadjzadeh
Roghayeh Pakdel
Parichehr Hayatdavoudi
Mohsen Nematy
author_facet Mousa-Al-Reza Hadjzadeh
Roghayeh Pakdel
Parichehr Hayatdavoudi
Mohsen Nematy
author_sort Mousa-Al-Reza Hadjzadeh
collection DOAJ
description Introduction: Fasting during the holy month of Ramadan is an obligation for all adult, healthy Muslims. As several studies have indicated, both fasting and energy restriction can alter thyroid hormone metabolism and affect the clinical features and well-being of hypothyroid patients. Hypothyroidism is more prevalent among women and the elderly. Its prevalence has been reported to be 4-8% of the general population. Despite the large body of animal research on fasting, few human studies have focused on Ramadan fasting and its impacts on hypothyroid patients. <br />Materials & Methods: PubMed and Google scholar databases were searched using keywords such as Ramadan, fasting, hypothyroidism, and food restriction. Animal and human studies, which were highly relevant to the topic, were selected. <br />Results: Four animal and 7 human studies were included in this article. We found that levothyroxine dosage should be increased for hypothyroid patients from the beginning of the month until 15-20 days after the end of Ramadan. <br />Discussion: Fasting can change the concentration of thyroid hormones, thyroid-stimulating hormone level, and the associated metabolisms both in animals and humans. As the results indicated, hypothyroid individuals, who fast during the month of Ramadan, particularly women and the elderly, may suffer from thyroid hormone changes. For these patients, levothyroxine dosage should be increased to 25-50 µg/per day from the beginning of Ramadan until 15-20 days after the end of this month. <br />Conclusion: An increased dose of levothyroxine during Ramadan is recommended for hypothyroid patients, particularly women and the elderly.
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spelling doaj.art-6dc69000daa64c3a8bc5e6e6ebc93fe22022-12-22T00:03:24ZengMashhad University of Medical SciencesJournal of Fasting and Health2345-25872345-25872014-05-0122808310.22038/jfh.2014.32543254Hypothyroidism and Ramadan fastingMousa-Al-Reza Hadjzadeh0Roghayeh Pakdel1Parichehr Hayatdavoudi2Mohsen Nematy3Neurocognitive Research Center, Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranNeurocognitive Research Center, Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranNeurocognitive Research Center, Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, IranIntroduction: Fasting during the holy month of Ramadan is an obligation for all adult, healthy Muslims. As several studies have indicated, both fasting and energy restriction can alter thyroid hormone metabolism and affect the clinical features and well-being of hypothyroid patients. Hypothyroidism is more prevalent among women and the elderly. Its prevalence has been reported to be 4-8% of the general population. Despite the large body of animal research on fasting, few human studies have focused on Ramadan fasting and its impacts on hypothyroid patients. <br />Materials & Methods: PubMed and Google scholar databases were searched using keywords such as Ramadan, fasting, hypothyroidism, and food restriction. Animal and human studies, which were highly relevant to the topic, were selected. <br />Results: Four animal and 7 human studies were included in this article. We found that levothyroxine dosage should be increased for hypothyroid patients from the beginning of the month until 15-20 days after the end of Ramadan. <br />Discussion: Fasting can change the concentration of thyroid hormones, thyroid-stimulating hormone level, and the associated metabolisms both in animals and humans. As the results indicated, hypothyroid individuals, who fast during the month of Ramadan, particularly women and the elderly, may suffer from thyroid hormone changes. For these patients, levothyroxine dosage should be increased to 25-50 µg/per day from the beginning of Ramadan until 15-20 days after the end of this month. <br />Conclusion: An increased dose of levothyroxine during Ramadan is recommended for hypothyroid patients, particularly women and the elderly.http://jnfh.mums.ac.ir/article_3254_de0721089637d14a9e73c60a8c09183b.pdfRamadanfastingHypothyroidismFood restriction
spellingShingle Mousa-Al-Reza Hadjzadeh
Roghayeh Pakdel
Parichehr Hayatdavoudi
Mohsen Nematy
Hypothyroidism and Ramadan fasting
Journal of Fasting and Health
Ramadan
fasting
Hypothyroidism
Food restriction
title Hypothyroidism and Ramadan fasting
title_full Hypothyroidism and Ramadan fasting
title_fullStr Hypothyroidism and Ramadan fasting
title_full_unstemmed Hypothyroidism and Ramadan fasting
title_short Hypothyroidism and Ramadan fasting
title_sort hypothyroidism and ramadan fasting
topic Ramadan
fasting
Hypothyroidism
Food restriction
url http://jnfh.mums.ac.ir/article_3254_de0721089637d14a9e73c60a8c09183b.pdf
work_keys_str_mv AT mousaalrezahadjzadeh hypothyroidismandramadanfasting
AT roghayehpakdel hypothyroidismandramadanfasting
AT parichehrhayatdavoudi hypothyroidismandramadanfasting
AT mohsennematy hypothyroidismandramadanfasting