Macrophage Coordination of the Interferon Lambda Immune Response
Lambda interferons (IFN-λs) are a major component of the innate immune defense to viruses, bacteria, and fungi. In human liver, IFN-λ not only drives antiviral responses, but also promotes inflammation and fibrosis in viral and non-viral diseases. Here we demonstrate that macrophages are primary res...
Main Authors: | Scott A. Read, Ratna Wijaya, Mehdi Ramezani-Moghadam, Enoch Tay, Steve Schibeci, Christopher Liddle, Vincent W. T. Lam, Lawrence Yuen, Mark W. Douglas, David Booth, Jacob George, Golo Ahlenstiel |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-11-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2019.02674/full |
Similar Items
-
Targeting Gut–Liver Axis for Treatment of Liver Fibrosis and Portal Hypertension
by: Eric Kalo, et al.
Published: (2021-09-01) -
Reprogramming—Evolving Path to Functional Surrogate β-Cells
by: Eric Kalo, et al.
Published: (2022-09-01) -
Time to broaden the screening strategy for chronic hepatitis B virus infection beyond the emergency department
by: Eric Kalo, et al.
Published: (2024-04-01) -
A Call for Implementation of an Evidence-Based, Quality Improvement, Decompensated Cirrhosis Discharge Care Bundle in Australia
by: Eric Kalo, et al.
Published: (2022-06-01) -
The Role of Gut-Derived Microbial Antigens on Liver Fibrosis Initiation and Progression
by: Dishen Chen, et al.
Published: (2019-10-01)