E3 Ubiquitin Ligase Regulators of Notch Receptor Endocytosis: From Flies to Humans

Notch is a developmental receptor, conserved in the evolution of the metazoa, which regulates cell fate proliferation and survival in numerous developmental contexts, and also regulates tissue renewal and repair in adult organisms. Notch is activated by proteolytic removal of its extracellular domai...

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Bibliographic Details
Main Authors: Raluca Revici, Samira Hosseini-Alghaderi, Fabienne Haslam, Rory Whiteford, Martin Baron
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/2/224

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