Green synthesis of highly functionalized heterocyclic bearing pyrazole moiety for cancer-targeted chemo/radioisotope therapy

Green synthesis of highly functionalized heterocyclic bearing pyrazole moiety for cancer-targeted chemo/radioisotope therapy

Abstract New derivatives of heterocyclic bearing pyrazole moiety were synthesized (eight new compounds from 2 to 9) via green synthesis methods (microwave-assisted and grinding techniques). 4,6-Diamino-1,3-diphenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile (2) shows high anti-cancer activity against...

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Bibliographic Details
Main Authors: Kurls E. Anwer, Galal H. Sayed, Basma M. Essa, Adli A. Selim
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Chemistry
Subjects:
Microwave
Grinding
Pyrazole
Radioiodination
Dual cancer therapy
Online Access:https://doi.org/10.1186/s13065-023-01053-7

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