Caffeic acid phenethyl ester (CAPE): pharmacodynamics and potential for therapeutic application
Caffeic acid phenethyl ester (CAPE) is the major pharmacologically-active component of some propolis types, rich in polyphenols, such as poplar propolis types. CAPE has the potential to be applied as a pharmaceutical as it possesses most of the pharmacological activities of propolis, such as anti-pr...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Pensoft Publishers
2019-10-01
|
| Series: | Pharmacia |
| Online Access: | https://pharmacia.pensoft.net/article/38573/download/pdf/ |
| _version_ | 1818792391012777984 |
|---|---|
| author | Yordan Yordanov |
| author_facet | Yordan Yordanov |
| author_sort | Yordan Yordanov |
| collection | DOAJ |
| description | Caffeic acid phenethyl ester (CAPE) is the major pharmacologically-active component of some propolis types, rich in polyphenols, such as poplar propolis types. CAPE has the potential to be applied as a pharmaceutical as it possesses most of the pharmacological activities of propolis, such as anti-proliferative, antioxidant, immunomodulatory, antidiabetic, anti-inflammatory and antimicrobial. Its advantage is that it lacks some of the downsides of total propolis extracts, such as inability for unified standardization, which is cornerstone for implementing its therapeutic potential as a drug. The current paper provides an overview on the pharmacodynamic principles of CAPE. We present literature search outcomes form ClinicalTrials.gov database and from scientific publications, available on Scopus and Crossref databases. We take a round view of CAPE’s potential therapeutic implications in light of approved drugs with related modes of action. |
| first_indexed | 2024-12-18T15:26:30Z |
| format | Article |
| id | doaj.art-6dd8d516913545a2932c3807a2cf48c0 |
| institution | Directory Open Access Journal |
| issn | 2603-557X |
| language | English |
| last_indexed | 2024-12-18T15:26:30Z |
| publishDate | 2019-10-01 |
| publisher | Pensoft Publishers |
| record_format | Article |
| series | Pharmacia |
| spelling | doaj.art-6dd8d516913545a2932c3807a2cf48c02022-12-21T21:03:14ZengPensoft PublishersPharmacia2603-557X2019-10-0166310711410.3897/pharmacia.66.e3857338573Caffeic acid phenethyl ester (CAPE): pharmacodynamics and potential for therapeutic applicationYordan Yordanov0Faculty of Pharmacy, Medical University - SofiaCaffeic acid phenethyl ester (CAPE) is the major pharmacologically-active component of some propolis types, rich in polyphenols, such as poplar propolis types. CAPE has the potential to be applied as a pharmaceutical as it possesses most of the pharmacological activities of propolis, such as anti-proliferative, antioxidant, immunomodulatory, antidiabetic, anti-inflammatory and antimicrobial. Its advantage is that it lacks some of the downsides of total propolis extracts, such as inability for unified standardization, which is cornerstone for implementing its therapeutic potential as a drug. The current paper provides an overview on the pharmacodynamic principles of CAPE. We present literature search outcomes form ClinicalTrials.gov database and from scientific publications, available on Scopus and Crossref databases. We take a round view of CAPE’s potential therapeutic implications in light of approved drugs with related modes of action.https://pharmacia.pensoft.net/article/38573/download/pdf/ |
| spellingShingle | Yordan Yordanov Caffeic acid phenethyl ester (CAPE): pharmacodynamics and potential for therapeutic application Pharmacia |
| title | Caffeic acid phenethyl ester (CAPE): pharmacodynamics and potential for therapeutic application |
| title_full | Caffeic acid phenethyl ester (CAPE): pharmacodynamics and potential for therapeutic application |
| title_fullStr | Caffeic acid phenethyl ester (CAPE): pharmacodynamics and potential for therapeutic application |
| title_full_unstemmed | Caffeic acid phenethyl ester (CAPE): pharmacodynamics and potential for therapeutic application |
| title_short | Caffeic acid phenethyl ester (CAPE): pharmacodynamics and potential for therapeutic application |
| title_sort | caffeic acid phenethyl ester cape pharmacodynamics and potential for therapeutic application |
| url | https://pharmacia.pensoft.net/article/38573/download/pdf/ |
| work_keys_str_mv | AT yordanyordanov caffeicacidphenethylestercapepharmacodynamicsandpotentialfortherapeuticapplication |