Blimp-1 Expression as an Exhaustion Transcription Factor in Chronic Lymphocytic Leukemia

Blimp-1 Expression as an Exhaustion Transcription Factor in Chronic Lymphocytic Leukemia

Background: PPreviously, it was shown that exhausted CD4+ and CD8+ T cells in chronic lymphocytic leukemia (CLL) co-express the two immune-inhibitory receptors, Tim-3 and PD-1. Present study investigated the expression of Blimp-1, a transcription factor involved in T cell exhaustion, in patients wit...

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Bibliographic Details
Main Authors:	Saeid Taghiloo, Esmaeil Allahmoradi, Mohsen Tehrani, Ghasem Janbabaei, Ramin Shekarriz, Hossein Asgarian-Omran
Format:	Article
Language:	English
Published:	Mazandaran University of Medical Sciences and Health Services 2017-08-01
Series:	Research in Molecular Medicine
Subjects:	Exhausted T cell Blimp-1 Chronic Lymphocytic Leukemia
Online Access:	http://rmm.mazums.ac.ir/browse.php?a_code=A-10-917-1&slc_lang=en&sid=1

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