Shelf-Life Evaluation and Lyophilization of PBCA-Based Polymeric Microbubbles

Shelf-Life Evaluation and Lyophilization of PBCA-Based Polymeric Microbubbles

Poly(<i>n</i>-butyl cyanoacrylate) microbubbles (PBCA-MB) are extensively employed for functional and molecular ultrasound (US) imaging, as well as for US-mediated drug delivery. To facilitate the use of PBCA-MB as a commercial platform for biomedical applications, it is important to sys...

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Bibliographic Details
Main Authors: Tarun Ojha, Vertika Pathak, Natascha Drude, Marek Weiler, Dirk Rommel, Stephan Rütten, Bertram Geinitz, Mies J. van Steenbergen, Gert Storm, Fabian Kiessling, Twan Lammers
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Pharmaceutics
Subjects:
PBCA
microbubbles
ultrasound
lyophilization
storage stability
drug retention
Online Access:https://www.mdpi.com/1999-4923/11/9/433

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