Safety of Exercise Testing in the Clinical Chinese Population
This 18-year cross-sectional study was conducted to provide data on the safety of exercise testing in the clinical Chinese population. We retrospectively identified exercise tests completed at Xiangya Hospital of Central South University from January 1, 2002 to December 31, 2019. From 43,130 unique...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-02-01
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| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2021.638682/full |
| _version_ | 1819059278824079360 |
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| author | Yaoshan Dun Yaoshan Dun Yaoshan Dun Thomas P. Olson Jeffrey W. Ripley-Gonzalez Kangling Xie Wenliang Zhang Ying Cai Yuan Liu Yanan Shen Nanjiang Zhou Xun Gong Suixin Liu Suixin Liu |
| author_facet | Yaoshan Dun Yaoshan Dun Yaoshan Dun Thomas P. Olson Jeffrey W. Ripley-Gonzalez Kangling Xie Wenliang Zhang Ying Cai Yuan Liu Yanan Shen Nanjiang Zhou Xun Gong Suixin Liu Suixin Liu |
| author_sort | Yaoshan Dun |
| collection | DOAJ |
| description | This 18-year cross-sectional study was conducted to provide data on the safety of exercise testing in the clinical Chinese population. We retrospectively identified exercise tests completed at Xiangya Hospital of Central South University from January 1, 2002 to December 31, 2019. From 43,130 unique individuals (50.9% female), a total of consecutive 50,142 tests (standard exercise testing 29,466; cardiopulmonary exercise testing 20,696) were retrieved. Demographics, patients' medical history, exercise testing characteristics, and exercise testing-related adverse events were described. Safety data is expressed as the number of adverse events per 10,000 tests, with 95% confidence interval. The average patients' age was 51 ± 13 years. The majority of patients were diagnosed with at least one disease (N = 44,941, 89.6%). Tests were maximal or symptom-limited. Common clinical symptoms included dizziness (6,822, 13.6%), chest pain or distress (2,760, 5.5%), and musculoskeletal limitations (2,507, 5.0%). Out of 50,142 tests, three adverse events occurred, including one sustained ventricular tachycardia, one sinus arrest with junctional escape rhythm at a rate of 28 bpm, and one syncopal event with fecal and urinary incontinence. The rate of adverse events was 0.8 events per 10,000 tests (95% confidence interval, 0.2–3.0) in men, 0.4 per 10,000 tests (0.7–2.2) in women, and 0.6 per 10,000 tests (0.21.8) total. This study represents the largest dataset analysis of exercise testing in the clinical Chinese population. Our results demonstrate that clinical exercise testing is safe, and the low rate of adverse events related to exercise testing might be due to the overall changes in clinical practice over time. |
| first_indexed | 2024-12-21T14:08:34Z |
| format | Article |
| id | doaj.art-6de3028ebcac4244873eb853338627bb |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-12-21T14:08:34Z |
| publishDate | 2021-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-6de3028ebcac4244873eb853338627bb2022-12-21T19:01:08ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2021-02-01810.3389/fcvm.2021.638682638682Safety of Exercise Testing in the Clinical Chinese PopulationYaoshan Dun0Yaoshan Dun1Yaoshan Dun2Thomas P. Olson3Jeffrey W. Ripley-Gonzalez4Kangling Xie5Wenliang Zhang6Ying Cai7Yuan Liu8Yanan Shen9Nanjiang Zhou10Xun Gong11Suixin Liu12Suixin Liu13Division of Cardiac Rehabilitation, Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital of Central South University, Changsha, ChinaDivision of Preventive Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United StatesDivision of Preventive Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United StatesDivision of Cardiac Rehabilitation, Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, ChinaDivision of Cardiac Rehabilitation, Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, ChinaDivision of Cardiac Rehabilitation, Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, ChinaDivision of Cardiac Rehabilitation, Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, ChinaDivision of Cardiac Rehabilitation, Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, ChinaDivision of Cardiac Rehabilitation, Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, ChinaDivision of Cardiac Rehabilitation, Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, ChinaDivision of Cardiac Rehabilitation, Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, ChinaDivision of Cardiac Rehabilitation, Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital of Central South University, Changsha, ChinaThis 18-year cross-sectional study was conducted to provide data on the safety of exercise testing in the clinical Chinese population. We retrospectively identified exercise tests completed at Xiangya Hospital of Central South University from January 1, 2002 to December 31, 2019. From 43,130 unique individuals (50.9% female), a total of consecutive 50,142 tests (standard exercise testing 29,466; cardiopulmonary exercise testing 20,696) were retrieved. Demographics, patients' medical history, exercise testing characteristics, and exercise testing-related adverse events were described. Safety data is expressed as the number of adverse events per 10,000 tests, with 95% confidence interval. The average patients' age was 51 ± 13 years. The majority of patients were diagnosed with at least one disease (N = 44,941, 89.6%). Tests were maximal or symptom-limited. Common clinical symptoms included dizziness (6,822, 13.6%), chest pain or distress (2,760, 5.5%), and musculoskeletal limitations (2,507, 5.0%). Out of 50,142 tests, three adverse events occurred, including one sustained ventricular tachycardia, one sinus arrest with junctional escape rhythm at a rate of 28 bpm, and one syncopal event with fecal and urinary incontinence. The rate of adverse events was 0.8 events per 10,000 tests (95% confidence interval, 0.2–3.0) in men, 0.4 per 10,000 tests (0.7–2.2) in women, and 0.6 per 10,000 tests (0.21.8) total. This study represents the largest dataset analysis of exercise testing in the clinical Chinese population. Our results demonstrate that clinical exercise testing is safe, and the low rate of adverse events related to exercise testing might be due to the overall changes in clinical practice over time.https://www.frontiersin.org/articles/10.3389/fcvm.2021.638682/fullsafetyexercise testingcardiopulmonary exercise testingcardiovascular diseaseclinical Chinese population |
| spellingShingle | Yaoshan Dun Yaoshan Dun Yaoshan Dun Thomas P. Olson Jeffrey W. Ripley-Gonzalez Kangling Xie Wenliang Zhang Ying Cai Yuan Liu Yanan Shen Nanjiang Zhou Xun Gong Suixin Liu Suixin Liu Safety of Exercise Testing in the Clinical Chinese Population Frontiers in Cardiovascular Medicine safety exercise testing cardiopulmonary exercise testing cardiovascular disease clinical Chinese population |
| title | Safety of Exercise Testing in the Clinical Chinese Population |
| title_full | Safety of Exercise Testing in the Clinical Chinese Population |
| title_fullStr | Safety of Exercise Testing in the Clinical Chinese Population |
| title_full_unstemmed | Safety of Exercise Testing in the Clinical Chinese Population |
| title_short | Safety of Exercise Testing in the Clinical Chinese Population |
| title_sort | safety of exercise testing in the clinical chinese population |
| topic | safety exercise testing cardiopulmonary exercise testing cardiovascular disease clinical Chinese population |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2021.638682/full |
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