Dynein catch bond as a mediator of codependent bidirectional cellular transport

Intracellular bidirectional transport of cargo on microtubule filaments is achieved by the collective action of oppositely directed dynein and kinesin motors. Experiments have found that in certain cases, inhibiting the activity of one type of motor results in an overall decline in the motility of t...

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Bibliographic Details
Main Authors: Palka Puri, Nisha Gupta, Sameep Chandel, Supriyo Naskar, Anil Nair, Abhishek Chaudhuri, Mithun K. Mitra, Sudipto Muhuri
Format: Article
Language:English
Published: American Physical Society 2019-09-01
Series:Physical Review Research
Online Access:http://doi.org/10.1103/PhysRevResearch.1.023019