PRIMARY OPEN-ANGLE GLAUCOMA IN ONCOLOGIC PATIENTS
Background: Glaucoma-induced visual impairment negatively influences quality of life of oncologic patients. Yet, tumor in itself and methods of its treatment may promote glaucoma progression. Aim: To study characteristics and course of primary open-angle glaucoma in oncologic patients. Materials and...
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| Format: | Article |
| Language: | Russian |
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MONIKI
2016-02-01
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| Series: | Alʹmanah Kliničeskoj Mediciny |
| Subjects: | |
| Online Access: | https://www.almclinmed.ru/jour/article/view/215 |
| _version_ | 1818653178979155968 |
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| author | A. A. Ryabtseva E. E. Grishina |
| author_facet | A. A. Ryabtseva E. E. Grishina |
| author_sort | A. A. Ryabtseva |
| collection | DOAJ |
| description | Background: Glaucoma-induced visual impairment negatively influences quality of life of oncologic patients. Yet, tumor in itself and methods of its treatment may promote glaucoma progression. Aim: To study characteristics and course of primary open-angle glaucoma in oncologic patients. Materials and methods: We analyzed case reports of 19 oncologic patients after primary open-angle glaucoma-related sinus trabeculectomy (34 eyes) and laser cyclopexy (1 eye). Diagnosed malignancies included colorectal cancer in 5 patients, uterine body and cervical cancer in 4 patients, chronic lymphocytic leukemia in 1 patient, renal cell carcinoma in 1 patient, adrenal cancer in 1 patient, prostatic cancer in 1 patient, breast cancer in 1 patient, vulvar cancer in 1 patient, tongue root cancer in 1 patient. Antiglaucomatous surgery was accomplished during the first 5 years from the diagnosis of tumor in 14 patients. In 9 patients, chemotherapy or hormone therapy was continued by the time of surgery. Follow-up of the patients was undertaken in 4–12 months after the antiglaucomatous operation; it included routine ophthalmological examination and dry eye syndrome functional tests. Results: Duration of postoperative period was 4 months or more. All patients had uveitis postoperatively. During late postoperative period, choroidal detachment was diagnosed in 4 patients. Bleb scarring was found in 2 patients. All patients received hypotensive treatment postoperatively including selective and non-selective beta-adrenergic blockers. Conjunctival and corneal xerosis was observed in all patients. Conclusion: In oncologic patients undergoing antiglaucomatous surgery, long-term (4 months or more) postoperative anti-inflammatory therapy is needed along with monthly ophthalmological follow-up during the first year after the operation. In patients with ongoing cytostatic drug treatment, artificial tear should be administrated. |
| first_indexed | 2024-12-17T02:33:47Z |
| format | Article |
| id | doaj.art-6de9b3e6891d46fdaee7a5e1a6cb244e |
| institution | Directory Open Access Journal |
| issn | 2072-0505 2587-9294 |
| language | Russian |
| last_indexed | 2024-12-17T02:33:47Z |
| publishDate | 2016-02-01 |
| publisher | MONIKI |
| record_format | Article |
| series | Alʹmanah Kliničeskoj Mediciny |
| spelling | doaj.art-6de9b3e6891d46fdaee7a5e1a6cb244e2022-12-21T22:06:54ZrusMONIKIAlʹmanah Kliničeskoj Mediciny2072-05052587-92942016-02-01036373910.18786/2072-0505-2015-36-37-39215PRIMARY OPEN-ANGLE GLAUCOMA IN ONCOLOGIC PATIENTSA. A. Ryabtseva0E. E. Grishina1Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Background: Glaucoma-induced visual impairment negatively influences quality of life of oncologic patients. Yet, tumor in itself and methods of its treatment may promote glaucoma progression. Aim: To study characteristics and course of primary open-angle glaucoma in oncologic patients. Materials and methods: We analyzed case reports of 19 oncologic patients after primary open-angle glaucoma-related sinus trabeculectomy (34 eyes) and laser cyclopexy (1 eye). Diagnosed malignancies included colorectal cancer in 5 patients, uterine body and cervical cancer in 4 patients, chronic lymphocytic leukemia in 1 patient, renal cell carcinoma in 1 patient, adrenal cancer in 1 patient, prostatic cancer in 1 patient, breast cancer in 1 patient, vulvar cancer in 1 patient, tongue root cancer in 1 patient. Antiglaucomatous surgery was accomplished during the first 5 years from the diagnosis of tumor in 14 patients. In 9 patients, chemotherapy or hormone therapy was continued by the time of surgery. Follow-up of the patients was undertaken in 4–12 months after the antiglaucomatous operation; it included routine ophthalmological examination and dry eye syndrome functional tests. Results: Duration of postoperative period was 4 months or more. All patients had uveitis postoperatively. During late postoperative period, choroidal detachment was diagnosed in 4 patients. Bleb scarring was found in 2 patients. All patients received hypotensive treatment postoperatively including selective and non-selective beta-adrenergic blockers. Conjunctival and corneal xerosis was observed in all patients. Conclusion: In oncologic patients undergoing antiglaucomatous surgery, long-term (4 months or more) postoperative anti-inflammatory therapy is needed along with monthly ophthalmological follow-up during the first year after the operation. In patients with ongoing cytostatic drug treatment, artificial tear should be administrated.https://www.almclinmed.ru/jour/article/view/215primary open-angle glaucomaoncologic patientuveitisdry eye syndrome |
| spellingShingle | A. A. Ryabtseva E. E. Grishina PRIMARY OPEN-ANGLE GLAUCOMA IN ONCOLOGIC PATIENTS Alʹmanah Kliničeskoj Mediciny primary open-angle glaucoma oncologic patient uveitis dry eye syndrome |
| title | PRIMARY OPEN-ANGLE GLAUCOMA IN ONCOLOGIC PATIENTS |
| title_full | PRIMARY OPEN-ANGLE GLAUCOMA IN ONCOLOGIC PATIENTS |
| title_fullStr | PRIMARY OPEN-ANGLE GLAUCOMA IN ONCOLOGIC PATIENTS |
| title_full_unstemmed | PRIMARY OPEN-ANGLE GLAUCOMA IN ONCOLOGIC PATIENTS |
| title_short | PRIMARY OPEN-ANGLE GLAUCOMA IN ONCOLOGIC PATIENTS |
| title_sort | primary open angle glaucoma in oncologic patients |
| topic | primary open-angle glaucoma oncologic patient uveitis dry eye syndrome |
| url | https://www.almclinmed.ru/jour/article/view/215 |
| work_keys_str_mv | AT aaryabtseva primaryopenangleglaucomainoncologicpatients AT eegrishina primaryopenangleglaucomainoncologicpatients |