Poly(I:C), a double stranded RNA analog, activates the anti-viral DNA sensors in buffalo fibroblasts

Poly(I:C), a double stranded RNA analog, activates the anti-viral DNA sensors in buffalo fibroblasts

Polyinosinic:polycytidylic acid or poly(I:C) is a double stranded RNA analog that is known for stimulating RNA sensing pathways in a variety of cell culture and animal models. Activation of nucleic acid sensing pathways lead to the up-regulation of Interferon-β which ultimately creates an antiviral...

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Bibliographic Details
Main Authors: Jatinder Singh Chera, Sushil Kumar, Amit Kumar Bairagi, Amit Kumar, Prakash Chandra, Ashutosh Vats, Murtaza Ali, Mayank Roshan, Ranjit Singh Kataria, Sachinandan De
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Veterinary Vaccine
Subjects:
Interferon
Innate
Fibroblast
Immunity
Antiviral
Poly(I:C)
Online Access:http://www.sciencedirect.com/science/article/pii/S2772535923000045

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