Muscimol Directly Activates the TREK-2 Channel Expressed in GABAergic Neurons through Its N-Terminus

Muscimol Directly Activates the TREK-2 Channel Expressed in GABAergic Neurons through Its N-Terminus

The two-pore domain K<sup>+</sup> (K<sub>2P</sub>) channel, which is involved in setting the resting membrane potential in neurons, is an essential target for receptor agonists. Activation of the γ-aminobutyric acid (GABA) receptors (GABA<sub>A</sub>R and GABA<...

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Bibliographic Details
Main Authors: Eun-Jin Kim, Oh-Sang Kwon, Chang-Gi Hur, Marie Merci Nyiramana, Dong-Kun Lee, Seong-Geun Hong, Jaehee Han, Dawon Kang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
γ-aminobutyric acid
γ-aminobutyric acid receptor
two-pore domain K<sup>+</sup> channel
Online Access:https://www.mdpi.com/1422-0067/22/17/9320

Internet

https://www.mdpi.com/1422-0067/22/17/9320

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