A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons

The limited size of some neuronal types and their entangled environment renders it difficult to study their transcription regulation. Here the authors present a comparative analysis of histone modifications and transcription in dopaminergic and serotonergic neurons and embryonic neural progenitors....

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Main Authors: Erik Södersten, Konstantinos Toskas, Vilma Rraklli, Katarina Tiklova, Åsa K. Björklund, Markus Ringnér, Thomas Perlmann, Johan Holmberg
Format: Article
Language:English
Published: Nature Portfolio 2018-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03538-9
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author Erik Södersten
Konstantinos Toskas
Vilma Rraklli
Katarina Tiklova
Åsa K. Björklund
Markus Ringnér
Thomas Perlmann
Johan Holmberg
author_facet Erik Södersten
Konstantinos Toskas
Vilma Rraklli
Katarina Tiklova
Åsa K. Björklund
Markus Ringnér
Thomas Perlmann
Johan Holmberg
author_sort Erik Södersten
collection DOAJ
description The limited size of some neuronal types and their entangled environment renders it difficult to study their transcription regulation. Here the authors present a comparative analysis of histone modifications and transcription in dopaminergic and serotonergic neurons and embryonic neural progenitors.
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spelling doaj.art-6df7c45a61984546bf5cda6b2f25f8ed2022-12-21T20:39:01ZengNature PortfolioNature Communications2041-17232018-03-019111610.1038/s41467-018-03538-9A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neuronsErik Södersten0Konstantinos Toskas1Vilma Rraklli2Katarina Tiklova3Åsa K. Björklund4Markus Ringnér5Thomas Perlmann6Johan Holmberg7Department of Cell and Molecular Biology, Ludwig Institute for Cancer Research, Karolinska InstitutetDepartment of Cell and Molecular Biology, Ludwig Institute for Cancer Research, Karolinska InstitutetDepartment of Cell and Molecular Biology, Ludwig Institute for Cancer Research, Karolinska InstitutetDepartment of Cell and Molecular Biology, Ludwig Institute for Cancer Research, Karolinska InstitutetDepartment for Cell and Molecular Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala UniversityDepartment of Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Lund UniversityDepartment of Cell and Molecular Biology, Ludwig Institute for Cancer Research, Karolinska InstitutetDepartment of Cell and Molecular Biology, Ludwig Institute for Cancer Research, Karolinska InstitutetThe limited size of some neuronal types and their entangled environment renders it difficult to study their transcription regulation. Here the authors present a comparative analysis of histone modifications and transcription in dopaminergic and serotonergic neurons and embryonic neural progenitors.https://doi.org/10.1038/s41467-018-03538-9
spellingShingle Erik Södersten
Konstantinos Toskas
Vilma Rraklli
Katarina Tiklova
Åsa K. Björklund
Markus Ringnér
Thomas Perlmann
Johan Holmberg
A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons
Nature Communications
title A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons
title_full A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons
title_fullStr A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons
title_full_unstemmed A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons
title_short A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons
title_sort comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons
url https://doi.org/10.1038/s41467-018-03538-9
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