Helios + Regulatory T cell frequencies are correlated with control of viral replication and recovery of absolute CD4 T cells counts in early HIV-1 infection

Helios + Regulatory T cell frequencies are correlated with control of viral replication and recovery of absolute CD4 T cells counts in early HIV-1 infection

Abstract Background The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation. Regulatory T cells (Tregs) have the potential to control systemic immune activation but also to suppress antigen specific T a...

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Bibliographic Details
Main Authors: Raquel Matavele Chissumba, Eduardo Namalango, Vânia Maphossa, Ivalda Macicame, Nilesh Bhatt, Christina Polyak, Merlin Robb, Nelson Michael, Ilesh Jani, Luc Kestens
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Immunology
Subjects:
Tregs
HIV early infection
Helios
Online Access:http://link.springer.com/article/10.1186/s12865-017-0235-7

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