Paracoccidioidomycosis in an Elderly Simulating Cholangiocarcinoma
Paracoccidioidomycosis, the most prevalent deep mycosis in Latin America, is caused by dimorphic species of the genus Paracoccidioides, affects predominantly male rural workers between 30-50 years of age and is an important cause of morbidity and mortality. It can present in two clinical forms: acut...
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| Format: | Article |
| Language: | English |
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Sociedade Portuguesa de Dermatologia e Venereologia
2021-10-01
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| Series: | Revista da Sociedade Portuguesa de Dermatologia e Venereologia |
| Subjects: | |
| Online Access: | https://revista.spdv.com.pt/index.php/spdv/article/view/1364 |
| _version_ | 1818790157757710336 |
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| author | Isabel Guerra Hisabella L. P. Simões Annair F. Valle Maria C. M. N. Castañon |
| author_facet | Isabel Guerra Hisabella L. P. Simões Annair F. Valle Maria C. M. N. Castañon |
| author_sort | Isabel Guerra |
| collection | DOAJ |
| description | Paracoccidioidomycosis, the most prevalent deep mycosis in Latin America, is caused by dimorphic species of the genus Paracoccidioides, affects predominantly male rural workers between 30-50 years of age and is an important cause of morbidity and mortality. It can present in two clinical forms: acute/subacute or chronic. In rare cases paracoccidioidomycosis may simulate neoplasia and must be considered as a differential diagnosis of intra-abdominal tumors in endemic areas. We report an exuberant case of subacute paracoccidioidomycosis in an elderly lady, although it is more frequent in the juvenile form. Multiple facial skin lesions were associated with a wasting syndrome and extensive adenopathy including in the hepatic area, causing bile duct dilatation simulating a cholangiocarcinoma. Skin histopathology was diagnostic and antifungal treatment allowed complete resolution of cutaneous and systemic lesions, thus highlighting the merit of the dermatologist, who was fundamental for the conclusive diagnosis and institution of specific therapy, resulting in a favorable outcome. |
| first_indexed | 2024-12-18T14:51:00Z |
| format | Article |
| id | doaj.art-6dfcd6cdde7a419a8c9b21fb579b0317 |
| institution | Directory Open Access Journal |
| issn | 2182-2395 2182-2409 |
| language | English |
| last_indexed | 2024-12-18T14:51:00Z |
| publishDate | 2021-10-01 |
| publisher | Sociedade Portuguesa de Dermatologia e Venereologia |
| record_format | Article |
| series | Revista da Sociedade Portuguesa de Dermatologia e Venereologia |
| spelling | doaj.art-6dfcd6cdde7a419a8c9b21fb579b03172022-12-21T21:04:10ZengSociedade Portuguesa de Dermatologia e VenereologiaRevista da Sociedade Portuguesa de Dermatologia e Venereologia2182-23952182-24092021-10-0179310.29021/spdv.79.3.1364Paracoccidioidomycosis in an Elderly Simulating CholangiocarcinomaIsabel Guerra0Hisabella L. P. Simões1Annair F. Valle2Maria C. M. N. Castañon3Dermatology, Federal University of Juiz de Fora Teaching Hospital - Juiz de Fora, BrazilDermatology, Federal University of Juiz de Fora Teaching Hospital - Juiz de Fora, Brazil.Dermatology, Federal University of Juiz de Fora Teaching Hospital - Juiz de Fora, BrazilDermatopatologia, Morphology Department - ICB - Federal University of Juiz de Fora - Juiz de Fora, Brazil.Paracoccidioidomycosis, the most prevalent deep mycosis in Latin America, is caused by dimorphic species of the genus Paracoccidioides, affects predominantly male rural workers between 30-50 years of age and is an important cause of morbidity and mortality. It can present in two clinical forms: acute/subacute or chronic. In rare cases paracoccidioidomycosis may simulate neoplasia and must be considered as a differential diagnosis of intra-abdominal tumors in endemic areas. We report an exuberant case of subacute paracoccidioidomycosis in an elderly lady, although it is more frequent in the juvenile form. Multiple facial skin lesions were associated with a wasting syndrome and extensive adenopathy including in the hepatic area, causing bile duct dilatation simulating a cholangiocarcinoma. Skin histopathology was diagnostic and antifungal treatment allowed complete resolution of cutaneous and systemic lesions, thus highlighting the merit of the dermatologist, who was fundamental for the conclusive diagnosis and institution of specific therapy, resulting in a favorable outcome.https://revista.spdv.com.pt/index.php/spdv/article/view/1364CholangiocarcinomaParacoccidioidomycosis |
| spellingShingle | Isabel Guerra Hisabella L. P. Simões Annair F. Valle Maria C. M. N. Castañon Paracoccidioidomycosis in an Elderly Simulating Cholangiocarcinoma Revista da Sociedade Portuguesa de Dermatologia e Venereologia Cholangiocarcinoma Paracoccidioidomycosis |
| title | Paracoccidioidomycosis in an Elderly Simulating Cholangiocarcinoma |
| title_full | Paracoccidioidomycosis in an Elderly Simulating Cholangiocarcinoma |
| title_fullStr | Paracoccidioidomycosis in an Elderly Simulating Cholangiocarcinoma |
| title_full_unstemmed | Paracoccidioidomycosis in an Elderly Simulating Cholangiocarcinoma |
| title_short | Paracoccidioidomycosis in an Elderly Simulating Cholangiocarcinoma |
| title_sort | paracoccidioidomycosis in an elderly simulating cholangiocarcinoma |
| topic | Cholangiocarcinoma Paracoccidioidomycosis |
| url | https://revista.spdv.com.pt/index.php/spdv/article/view/1364 |
| work_keys_str_mv | AT isabelguerra paracoccidioidomycosisinanelderlysimulatingcholangiocarcinoma AT hisabellalpsimoes paracoccidioidomycosisinanelderlysimulatingcholangiocarcinoma AT annairfvalle paracoccidioidomycosisinanelderlysimulatingcholangiocarcinoma AT mariacmncastanon paracoccidioidomycosisinanelderlysimulatingcholangiocarcinoma |