Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients
Lynggaard et al. profile the salivary proteome and metaproteome in patients with head and neck cancer who have received radiation therapy and an intraglandular mesenchymal stem cell (MSC) treatment for radiation-induced xerostomia and in healthy controls. MSC therapy impacts the composition of the s...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-12-01
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| Series: | Communications Medicine |
| Online Access: | https://doi.org/10.1038/s43856-022-00223-3 |
| _version_ | 1811302010037731328 |
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| author | Charlotte Duch Lynggaard Rosa Jersie-Christensen Morten Juhl Siri Beier Jensen Christian Grønhøj Jacob Melchiors Søren Jacobsen Michael Møller-Hansen Mikkel Herly Annette Ekblond Jens Kastrup Anne Fischer-Nielsen Daniel Belstrøm Christian von Buchwald |
| author_facet | Charlotte Duch Lynggaard Rosa Jersie-Christensen Morten Juhl Siri Beier Jensen Christian Grønhøj Jacob Melchiors Søren Jacobsen Michael Møller-Hansen Mikkel Herly Annette Ekblond Jens Kastrup Anne Fischer-Nielsen Daniel Belstrøm Christian von Buchwald |
| author_sort | Charlotte Duch Lynggaard |
| collection | DOAJ |
| description | Lynggaard et al. profile the salivary proteome and metaproteome in patients with head and neck cancer who have received radiation therapy and an intraglandular mesenchymal stem cell (MSC) treatment for radiation-induced xerostomia and in healthy controls. MSC therapy impacts the composition of the salivary proteome in the longer-term. |
| first_indexed | 2024-04-13T07:20:21Z |
| format | Article |
| id | doaj.art-6dfdb68785ce454eb915038edeb94bf1 |
| institution | Directory Open Access Journal |
| issn | 2730-664X |
| language | English |
| last_indexed | 2024-04-13T07:20:21Z |
| publishDate | 2022-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Medicine |
| spelling | doaj.art-6dfdb68785ce454eb915038edeb94bf12022-12-22T02:56:39ZengNature PortfolioCommunications Medicine2730-664X2022-12-012111210.1038/s43856-022-00223-3Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patientsCharlotte Duch Lynggaard0Rosa Jersie-Christensen1Morten Juhl2Siri Beier Jensen3Christian Grønhøj4Jacob Melchiors5Søren Jacobsen6Michael Møller-Hansen7Mikkel Herly8Annette Ekblond9Jens Kastrup10Anne Fischer-Nielsen11Daniel Belstrøm12Christian von Buchwald13Department of Otolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University HospitalDepartment of Science and Environment, Roskilde UniversityCardiology Stem Cell Centre, Rigshospitalet, Copenhagen University HospitalDepartment of Dentistry and Oral Health, Aarhus UniversityDepartment of Otolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University HospitalDepartment of Otolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University HospitalDepartment of Clinical Medicine, Copenhagen UniversityDepartment of Ophthalmology, Rigshospitalet, Copenhagen University HospitalDepartment of Plastic Surgery and Burns Treatment, Rigshospitalet, Copenhagen University HospitalCardiology Stem Cell Centre, Rigshospitalet, Copenhagen University HospitalCardiology Stem Cell Centre, Rigshospitalet, Copenhagen University HospitalDepartment of Clinical Immunology, Rigshospitalet, Copenhagen University HospitalDepartment of Odontology, Section for Clinical Oral Microbiology, Faculty of Health and Medical Sciences, University of CopenhagenDepartment of Otolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University HospitalLynggaard et al. profile the salivary proteome and metaproteome in patients with head and neck cancer who have received radiation therapy and an intraglandular mesenchymal stem cell (MSC) treatment for radiation-induced xerostomia and in healthy controls. MSC therapy impacts the composition of the salivary proteome in the longer-term.https://doi.org/10.1038/s43856-022-00223-3 |
| spellingShingle | Charlotte Duch Lynggaard Rosa Jersie-Christensen Morten Juhl Siri Beier Jensen Christian Grønhøj Jacob Melchiors Søren Jacobsen Michael Møller-Hansen Mikkel Herly Annette Ekblond Jens Kastrup Anne Fischer-Nielsen Daniel Belstrøm Christian von Buchwald Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients Communications Medicine |
| title | Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients |
| title_full | Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients |
| title_fullStr | Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients |
| title_full_unstemmed | Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients |
| title_short | Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients |
| title_sort | intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients |
| url | https://doi.org/10.1038/s43856-022-00223-3 |
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