The clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma
Abstract Background To examine the clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphoma. Methods Twenty-one patients with 26 eyes diagnosed with ocular adnexal MALT lymphoma (26 eyes), who were treated in Hokkaido University Hospit...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-05-01
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| Series: | Radiation Oncology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13014-018-1045-7 |
| _version_ | 1818310955225841664 |
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| author | Kanae Fukutsu Satoru Kase Kan Ishijima Rumiko Kinoshita Susumu Ishida |
| author_facet | Kanae Fukutsu Satoru Kase Kan Ishijima Rumiko Kinoshita Susumu Ishida |
| author_sort | Kanae Fukutsu |
| collection | DOAJ |
| description | Abstract Background To examine the clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphoma. Methods Twenty-one patients with 26 eyes diagnosed with ocular adnexal MALT lymphoma (26 eyes), who were treated in Hokkaido University Hospital, were retrospectively reviewed based on medical records. Results Out of the 21 patients, 16 patients (21 eyes) received radiation therapy (RT) with a total dose of 30 Gy. All cases eventually achieved complete remission. Eight of these patients (11 eyes: 52.3%) required cataract surgery after RT. The mean age at surgery was 56.8 (40–70) years. The mean latency between RT and the indication for surgery was 43.3 months. The percentage of females was significantly higher in patients who required surgery (P < 0.01), compared with those without surgery. The eyes of patients who received bolus technique on radiation treatment developed cataract more frequently (P < 0.05). In contrast, none of the patients without RT required cataract surgery. Conclusions Patients with ocular adnexal MALT lymphoma who underwent surgery for radiation cataract were seen more often in relatively young, female patients, and surgery was required about 3 years after RT. A long-term observation may be needed for patients after RT for a tumor. A female sex and the bolus technique may be risk factors for radiation cataract. |
| first_indexed | 2024-12-13T07:54:17Z |
| format | Article |
| id | doaj.art-6dfe5e274ca94b5e8f83a31f45fd3d0c |
| institution | Directory Open Access Journal |
| issn | 1748-717X |
| language | English |
| last_indexed | 2024-12-13T07:54:17Z |
| publishDate | 2018-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Radiation Oncology |
| spelling | doaj.art-6dfe5e274ca94b5e8f83a31f45fd3d0c2022-12-21T23:54:34ZengBMCRadiation Oncology1748-717X2018-05-011311710.1186/s13014-018-1045-7The clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue lymphomaKanae Fukutsu0Satoru Kase1Kan Ishijima2Rumiko Kinoshita3Susumu Ishida4Department of Ophthalmology, Hokkaido University Graduate School of MedicineDepartment of Ophthalmology, Hokkaido University Graduate School of MedicineDepartment of Ophthalmology, Hokkaido University Graduate School of MedicineDepartment of Radiation Oncology, Hokkaido University HospitalDepartment of Ophthalmology, Hokkaido University Graduate School of MedicineAbstract Background To examine the clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphoma. Methods Twenty-one patients with 26 eyes diagnosed with ocular adnexal MALT lymphoma (26 eyes), who were treated in Hokkaido University Hospital, were retrospectively reviewed based on medical records. Results Out of the 21 patients, 16 patients (21 eyes) received radiation therapy (RT) with a total dose of 30 Gy. All cases eventually achieved complete remission. Eight of these patients (11 eyes: 52.3%) required cataract surgery after RT. The mean age at surgery was 56.8 (40–70) years. The mean latency between RT and the indication for surgery was 43.3 months. The percentage of females was significantly higher in patients who required surgery (P < 0.01), compared with those without surgery. The eyes of patients who received bolus technique on radiation treatment developed cataract more frequently (P < 0.05). In contrast, none of the patients without RT required cataract surgery. Conclusions Patients with ocular adnexal MALT lymphoma who underwent surgery for radiation cataract were seen more often in relatively young, female patients, and surgery was required about 3 years after RT. A long-term observation may be needed for patients after RT for a tumor. A female sex and the bolus technique may be risk factors for radiation cataract.http://link.springer.com/article/10.1186/s13014-018-1045-7Ocular adnexaMALT lymphomaFemaleBolusRadiation cataract |
| spellingShingle | Kanae Fukutsu Satoru Kase Kan Ishijima Rumiko Kinoshita Susumu Ishida The clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma Radiation Oncology Ocular adnexa MALT lymphoma Female Bolus Radiation cataract |
| title | The clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma |
| title_full | The clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma |
| title_fullStr | The clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma |
| title_full_unstemmed | The clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma |
| title_short | The clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma |
| title_sort | clinical features of radiation cataract in patients with ocular adnexal mucosa associated lymphoid tissue lymphoma |
| topic | Ocular adnexa MALT lymphoma Female Bolus Radiation cataract |
| url | http://link.springer.com/article/10.1186/s13014-018-1045-7 |
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