Dyslipidemia in dialysis patients

In order to evaluate the lipid profiles of dialysis patients, we retrospectively reviewed all the chronic kidney disease (CKD) patients on chronic hemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD), followed up between June 2004 and May 2005, in two tertiary hospitals in Riyadh, S...

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Main Authors: Ahmed H Mitwalli, Awatif A Alam, Jamal S Al Wakeel, Arthur C Isnani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Saudi Journal of Kidney Diseases and Transplantation
Online Access:http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=689;epage=694;aulast=Mitwalli
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author Ahmed H Mitwalli
Awatif A Alam
Jamal S Al Wakeel
Arthur C Isnani
author_facet Ahmed H Mitwalli
Awatif A Alam
Jamal S Al Wakeel
Arthur C Isnani
author_sort Ahmed H Mitwalli
collection DOAJ
description In order to evaluate the lipid profiles of dialysis patients, we retrospectively reviewed all the chronic kidney disease (CKD) patients on chronic hemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD), followed up between June 2004 and May 2005, in two tertiary hospitals in Riyadh, Saudi Arabia. There were 380 patients including 206 (54.2%) females and the mean age of the patients was 45.9 ± 15.8 years. The mean dialysis duration was 65.0 ± 58.3 months. Diabetes was present in 97 (25.5%) of the patients and hypertension in 84 (22.1%). Younger patients had more disturbed lipid profile than elderly patients, and females had higher lipid values than males. The CAPD patients had worse lipid profile than those on HD, irrespective of age, sex and duration of dialysis. The presence of diabetes, hypertension, smoking and cardiovascular disease (CVD) all contributed to the worsening of lipid profiles of our patients. Dialysis patients showed improvement in lipid profile initially followed by gradual deterioration. We conclude that dyslipidemia, which increases the risk of CVD by increasing atherogenesis, progresses over time in dialysis patients and becomes worse in CAPD patients.
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spelling doaj.art-6e0546b5715546c3a473fa60bb7408232022-12-21T17:57:58ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422011-01-01224689694Dyslipidemia in dialysis patientsAhmed H MitwalliAwatif A AlamJamal S Al WakeelArthur C IsnaniIn order to evaluate the lipid profiles of dialysis patients, we retrospectively reviewed all the chronic kidney disease (CKD) patients on chronic hemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD), followed up between June 2004 and May 2005, in two tertiary hospitals in Riyadh, Saudi Arabia. There were 380 patients including 206 (54.2%) females and the mean age of the patients was 45.9 ± 15.8 years. The mean dialysis duration was 65.0 ± 58.3 months. Diabetes was present in 97 (25.5%) of the patients and hypertension in 84 (22.1%). Younger patients had more disturbed lipid profile than elderly patients, and females had higher lipid values than males. The CAPD patients had worse lipid profile than those on HD, irrespective of age, sex and duration of dialysis. The presence of diabetes, hypertension, smoking and cardiovascular disease (CVD) all contributed to the worsening of lipid profiles of our patients. Dialysis patients showed improvement in lipid profile initially followed by gradual deterioration. We conclude that dyslipidemia, which increases the risk of CVD by increasing atherogenesis, progresses over time in dialysis patients and becomes worse in CAPD patients.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=689;epage=694;aulast=Mitwalli
spellingShingle Ahmed H Mitwalli
Awatif A Alam
Jamal S Al Wakeel
Arthur C Isnani
Dyslipidemia in dialysis patients
Saudi Journal of Kidney Diseases and Transplantation
title Dyslipidemia in dialysis patients
title_full Dyslipidemia in dialysis patients
title_fullStr Dyslipidemia in dialysis patients
title_full_unstemmed Dyslipidemia in dialysis patients
title_short Dyslipidemia in dialysis patients
title_sort dyslipidemia in dialysis patients
url http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=689;epage=694;aulast=Mitwalli
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AT arthurcisnani dyslipidemiaindialysispatients