Phytochemical Study of Stem and Leaf of <i>Clausena lansium</i>
<i>Clausena lansium</i> Lour. Skeels (Rutaceae) is widely distributed in South China and has historically been used as a traditional medicine in local healthcare systems. Although the characteristic components (carbazole alkaloids and coumarins) of <i>C. lansium</i> have been...
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MDPI AG
2019-08-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/24/17/3124 |
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| author | Wenwen Peng Xiaoxiang Fu Yuyan Li Zhonghua Xiong Xugen Shi Fang Zhang Guanghua Huo Baotong Li |
| author_facet | Wenwen Peng Xiaoxiang Fu Yuyan Li Zhonghua Xiong Xugen Shi Fang Zhang Guanghua Huo Baotong Li |
| author_sort | Wenwen Peng |
| collection | DOAJ |
| description | <i>Clausena lansium</i> Lour. Skeels (Rutaceae) is widely distributed in South China and has historically been used as a traditional medicine in local healthcare systems. Although the characteristic components (carbazole alkaloids and coumarins) of <i>C. lansium</i> have been found to possess a wide variety of biological activities, little attention has been paid toward the other components of this plant. In the current study, phytochemical analysis of isolates from a water-soluble stem and leaf extract of <i>C. lansium</i> led to the identification of 12 compounds, including five aromatic glycosides, four sesquiterpene glycosides, two dihydrofuranocoumarin glycosides, and one adenosine. All compounds were isolated for the first time from the genus <i>Clausena</i>, including a new aromatic glycoside (<b>1</b>), a new dihydrofuranocoumarin glycoside (<b>6</b>), and two new sesquiterpene glycosides (<b>8</b> and <b>9</b>). The phytochemical structures of the isolates were elucidated using spectroscopic analyses including NMR and MS. The existence of these compounds demonstrates the taxonomic significance of <i>C. lansium</i> in the genus <i>Clausena</i> and suggests that some glycosides from this plant probably play a role in the anticancer activity of <i>C. lansium</i> to some extent. |
| first_indexed | 2024-12-12T20:02:19Z |
| format | Article |
| id | doaj.art-6e0959f362f84505bd6c9a137aa39028 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-12T20:02:19Z |
| publishDate | 2019-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-6e0959f362f84505bd6c9a137aa390282022-12-22T00:13:43ZengMDPI AGMolecules1420-30492019-08-012417312410.3390/molecules24173124molecules24173124Phytochemical Study of Stem and Leaf of <i>Clausena lansium</i>Wenwen Peng0Xiaoxiang Fu1Yuyan Li2Zhonghua Xiong3Xugen Shi4Fang Zhang5Guanghua Huo6Baotong Li7Jiangxi Key Laboratory for Conservation and Utilization of Fungal Resources, Jiangxi Agricultural University, Nanchang 330045, ChinaCollege of Agriculture, Jiangxi Agricultural University, Nanchang 330045, ChinaCollege of Agriculture, Jiangxi Agricultural University, Nanchang 330045, ChinaCollege of Agriculture, Jiangxi Agricultural University, Nanchang 330045, ChinaCollege of Agriculture, Jiangxi Agricultural University, Nanchang 330045, ChinaCollege of Agriculture, Jiangxi Agricultural University, Nanchang 330045, ChinaJiangxi Key Laboratory for Conservation and Utilization of Fungal Resources, Jiangxi Agricultural University, Nanchang 330045, ChinaSchool of Land Resources and Environment, Jiangxi Agricultural University, Nanchang 330045, China<i>Clausena lansium</i> Lour. Skeels (Rutaceae) is widely distributed in South China and has historically been used as a traditional medicine in local healthcare systems. Although the characteristic components (carbazole alkaloids and coumarins) of <i>C. lansium</i> have been found to possess a wide variety of biological activities, little attention has been paid toward the other components of this plant. In the current study, phytochemical analysis of isolates from a water-soluble stem and leaf extract of <i>C. lansium</i> led to the identification of 12 compounds, including five aromatic glycosides, four sesquiterpene glycosides, two dihydrofuranocoumarin glycosides, and one adenosine. All compounds were isolated for the first time from the genus <i>Clausena</i>, including a new aromatic glycoside (<b>1</b>), a new dihydrofuranocoumarin glycoside (<b>6</b>), and two new sesquiterpene glycosides (<b>8</b> and <b>9</b>). The phytochemical structures of the isolates were elucidated using spectroscopic analyses including NMR and MS. The existence of these compounds demonstrates the taxonomic significance of <i>C. lansium</i> in the genus <i>Clausena</i> and suggests that some glycosides from this plant probably play a role in the anticancer activity of <i>C. lansium</i> to some extent.https://www.mdpi.com/1420-3049/24/17/3124<i>Clausena lansium</i>aromatic glycosidessesquiterpene glycosidesdihydrofuranocoumarin glycosides |
| spellingShingle | Wenwen Peng Xiaoxiang Fu Yuyan Li Zhonghua Xiong Xugen Shi Fang Zhang Guanghua Huo Baotong Li Phytochemical Study of Stem and Leaf of <i>Clausena lansium</i> Molecules <i>Clausena lansium</i> aromatic glycosides sesquiterpene glycosides dihydrofuranocoumarin glycosides |
| title | Phytochemical Study of Stem and Leaf of <i>Clausena lansium</i> |
| title_full | Phytochemical Study of Stem and Leaf of <i>Clausena lansium</i> |
| title_fullStr | Phytochemical Study of Stem and Leaf of <i>Clausena lansium</i> |
| title_full_unstemmed | Phytochemical Study of Stem and Leaf of <i>Clausena lansium</i> |
| title_short | Phytochemical Study of Stem and Leaf of <i>Clausena lansium</i> |
| title_sort | phytochemical study of stem and leaf of i clausena lansium i |
| topic | <i>Clausena lansium</i> aromatic glycosides sesquiterpene glycosides dihydrofuranocoumarin glycosides |
| url | https://www.mdpi.com/1420-3049/24/17/3124 |
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