A Comparative Event-Related Potentials Study between Alcohol Use Disorder, Gambling Disorder and Healthy Control Subjects through a Contextual Go/NoGo Task
(1) Background: Inhibitory and rewarding processes that mediate attentional biases to addiction-related cues may slightly differ between patients suffering from alcohol use (AUD) or gambling (GD) disorder. (2) Methods: 23 AUD inpatients, 19 GD patients, and 22 healthy controls performed four separat...
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| Format: | Article |
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MDPI AG
2023-04-01
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| Series: | Biology |
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| Online Access: | https://www.mdpi.com/2079-7737/12/5/643 |
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| author | Macha Dubuson Xavier Noël Charles Kornreich Catherine Hanak Mélanie Saeremans Salvatore Campanella |
| author_facet | Macha Dubuson Xavier Noël Charles Kornreich Catherine Hanak Mélanie Saeremans Salvatore Campanella |
| author_sort | Macha Dubuson |
| collection | DOAJ |
| description | (1) Background: Inhibitory and rewarding processes that mediate attentional biases to addiction-related cues may slightly differ between patients suffering from alcohol use (AUD) or gambling (GD) disorder. (2) Methods: 23 AUD inpatients, 19 GD patients, and 22 healthy controls performed four separate Go/NoGo tasks, in, respectively, an alcohol, gambling, food, and neutral long-lasting cueing context during the recording of event-related potentials (ERPs). (3) Results: AUD patients showed a poorer inhibitory performance than controls (slower response latencies, lower N2d, and delayed P3d components). In addition, AUD patients showed a preserved inhibitory performance in the alcohol-related context (but a more disrupted one in the food-related context), while GD patients showed a specific inhibitory deficit in the game-related context, both indexed by N2d amplitude modulations. (4) Conclusions: Despite sharing common addiction-related mechanisms, AUD and GD patients showed different patterns of response to (non-)rewarding cues that should be taken into account in the therapeutic context. |
| first_indexed | 2024-03-11T03:55:43Z |
| format | Article |
| id | doaj.art-6e0d0fb8badc42cbbb8f256f3fb33910 |
| institution | Directory Open Access Journal |
| issn | 2079-7737 |
| language | English |
| last_indexed | 2024-03-11T03:55:43Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology |
| spelling | doaj.art-6e0d0fb8badc42cbbb8f256f3fb339102023-11-18T00:32:21ZengMDPI AGBiology2079-77372023-04-0112564310.3390/biology12050643A Comparative Event-Related Potentials Study between Alcohol Use Disorder, Gambling Disorder and Healthy Control Subjects through a Contextual Go/NoGo TaskMacha Dubuson0Xavier Noël1Charles Kornreich2Catherine Hanak3Mélanie Saeremans4Salvatore Campanella5Laboratoire de Psychologie Médicale et d’Addictologie, Faculty of Medicine, Université Libre de Bruxelles (ULB), CHU Brugmann, Psychiatry Institute, 4 Place Vangehuchten, ULB Neuroscience Institute (UNI), 1020 Brussels, BelgiumLaboratoire de Psychologie Médicale et d’Addictologie, Faculty of Medicine, Université Libre de Bruxelles (ULB), CHU Brugmann, Psychiatry Institute, 4 Place Vangehuchten, ULB Neuroscience Institute (UNI), 1020 Brussels, BelgiumLaboratoire de Psychologie Médicale et d’Addictologie, Faculty of Medicine, Université Libre de Bruxelles (ULB), CHU Brugmann, Psychiatry Institute, 4 Place Vangehuchten, ULB Neuroscience Institute (UNI), 1020 Brussels, BelgiumLaboratoire de Psychologie Médicale et d’Addictologie, Faculty of Medicine, Université Libre de Bruxelles (ULB), CHU Brugmann, Psychiatry Institute, 4 Place Vangehuchten, ULB Neuroscience Institute (UNI), 1020 Brussels, BelgiumLaboratoire de Psychologie Médicale et d’Addictologie, Faculty of Medicine, Université Libre de Bruxelles (ULB), CHU Brugmann, Psychiatry Institute, 4 Place Vangehuchten, ULB Neuroscience Institute (UNI), 1020 Brussels, BelgiumLaboratoire de Psychologie Médicale et d’Addictologie, Faculty of Medicine, Université Libre de Bruxelles (ULB), CHU Brugmann, Psychiatry Institute, 4 Place Vangehuchten, ULB Neuroscience Institute (UNI), 1020 Brussels, Belgium(1) Background: Inhibitory and rewarding processes that mediate attentional biases to addiction-related cues may slightly differ between patients suffering from alcohol use (AUD) or gambling (GD) disorder. (2) Methods: 23 AUD inpatients, 19 GD patients, and 22 healthy controls performed four separate Go/NoGo tasks, in, respectively, an alcohol, gambling, food, and neutral long-lasting cueing context during the recording of event-related potentials (ERPs). (3) Results: AUD patients showed a poorer inhibitory performance than controls (slower response latencies, lower N2d, and delayed P3d components). In addition, AUD patients showed a preserved inhibitory performance in the alcohol-related context (but a more disrupted one in the food-related context), while GD patients showed a specific inhibitory deficit in the game-related context, both indexed by N2d amplitude modulations. (4) Conclusions: Despite sharing common addiction-related mechanisms, AUD and GD patients showed different patterns of response to (non-)rewarding cues that should be taken into account in the therapeutic context.https://www.mdpi.com/2079-7737/12/5/643addictionevent-related potentialinhibition responseGo/NoGo taskalcohol use disordergambling disorder |
| spellingShingle | Macha Dubuson Xavier Noël Charles Kornreich Catherine Hanak Mélanie Saeremans Salvatore Campanella A Comparative Event-Related Potentials Study between Alcohol Use Disorder, Gambling Disorder and Healthy Control Subjects through a Contextual Go/NoGo Task Biology addiction event-related potential inhibition response Go/NoGo task alcohol use disorder gambling disorder |
| title | A Comparative Event-Related Potentials Study between Alcohol Use Disorder, Gambling Disorder and Healthy Control Subjects through a Contextual Go/NoGo Task |
| title_full | A Comparative Event-Related Potentials Study between Alcohol Use Disorder, Gambling Disorder and Healthy Control Subjects through a Contextual Go/NoGo Task |
| title_fullStr | A Comparative Event-Related Potentials Study between Alcohol Use Disorder, Gambling Disorder and Healthy Control Subjects through a Contextual Go/NoGo Task |
| title_full_unstemmed | A Comparative Event-Related Potentials Study between Alcohol Use Disorder, Gambling Disorder and Healthy Control Subjects through a Contextual Go/NoGo Task |
| title_short | A Comparative Event-Related Potentials Study between Alcohol Use Disorder, Gambling Disorder and Healthy Control Subjects through a Contextual Go/NoGo Task |
| title_sort | comparative event related potentials study between alcohol use disorder gambling disorder and healthy control subjects through a contextual go nogo task |
| topic | addiction event-related potential inhibition response Go/NoGo task alcohol use disorder gambling disorder |
| url | https://www.mdpi.com/2079-7737/12/5/643 |
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