Apixaban and clopidogrel in a fixed-dose combination: Formulation and in vitro evaluation

Apixaban and clopidogrel in a fixed-dose combination: Formulation and in vitro evaluation

Fixed-dose combination (FDC) products represent a novel, safe, and cost-effective formulation. Combined use of anticoagulant and antiplatelet medications is common among comorbid cardiovascular patients. This study aimed to formulate FDC tablets for Apixaban and Clopidogrel, as prophylaxis and treat...

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Bibliographic Details
Main Authors: Ni'meh Al-Shami, Hani Naseef, Feras Kanaze
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Saudi Pharmaceutical Journal
Subjects:
Fixed-dose combination tablets
Apixaban
Clopidogrel
Extended-release
Factorial design
In vitro dissolution
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016424001397

Internet

http://www.sciencedirect.com/science/article/pii/S1319016424001397

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