Lactoferrin Inhibition of the Complex Formation between ACE2 Receptor and SARS CoV-2 Recognition Binding Domain

Lactoferrin Inhibition of the Complex Formation between ACE2 Receptor and SARS CoV-2 Recognition Binding Domain

The present investigation focuses on the analysis of the interactions among human lactoferrin (LF), SARS-CoV-2 receptor-binding domain (RBD) and human angiotensin-converting enzyme 2 (ACE2) receptor in order to assess possible mutual interactions that could provide a molecular basis of the reported...

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Bibliographic Details
Main Authors: Roberta Piacentini, Laura Centi, Mattia Miotto, Edoardo Milanetti, Lorenzo Di Rienzo, Martina Pitea, Paolo Piazza, Giancarlo Ruocco, Alberto Boffi, Giacomo Parisi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
SARS-CoV-2 receptor-binding domain (RBD)
angiotensin-converting enzyme 2 (ACE2)
lactoferrin
biolayer interferometry
nanoparticle enhanced turbidimetry
kinetic analysis
Online Access:https://www.mdpi.com/1422-0067/23/10/5436

Internet

https://www.mdpi.com/1422-0067/23/10/5436

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