Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study
Abstract Background Bladder cancer is one of the most common urinary tract cancers. This study aims to estimate the survival rate of patients with bladder cancer according to the Cox proportional hazards model based on some key relevant variables. Methods In this retrospective population-based cohor...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-12-01
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| Series: | BMC Urology |
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| Online Access: | https://doi.org/10.1186/s12894-020-00769-1 |
| _version_ | 1819061590888022016 |
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| author | Mozhdeh Amiri Sofimajidpour Heshmatollah Nader Esmaeilnasab Jamshid Khoubi Ebrahim Ghaderi Daem Roshani |
| author_facet | Mozhdeh Amiri Sofimajidpour Heshmatollah Nader Esmaeilnasab Jamshid Khoubi Ebrahim Ghaderi Daem Roshani |
| author_sort | Mozhdeh Amiri |
| collection | DOAJ |
| description | Abstract Background Bladder cancer is one of the most common urinary tract cancers. This study aims to estimate the survival rate of patients with bladder cancer according to the Cox proportional hazards model based on some key relevant variables. Methods In this retrospective population-based cohort study that explores the survival of patients with bladder cancer and its related factors, we first collected demographic information and medical records of 321 patients with bladder cancer through in-person and telephone interviews. Then, in the analysis phase, Kaplan–Meier method and log-rank test were used to draw the survival curve, compare the groups, and explore the effect of risk factors on the patient survival rate using Cox proportional hazards model. Results The median survival rate of patients was 63.2 (54.7–72) months and one, three and five-year survival rates were 87%, 68% and 54%, respectively. The results of multiple analyses using Cox's proportional hazards model revealed that variables of sex (male gender) (HR = 11.8, 95% CI: 0.4–100.7), more than 65 year of age (HR = 4.1, 95% CI: 0.4–11), occupation, income level, (HR = 0.4, 95% CI: 0.2–0.8), well differentiated tumor grade (HR = 3.2, 95% CI: 1.7–6) and disease stage influenced the survival rate of patients (p < 0.05). Conclusion The survival rate of patients with bladder cancer in Kurdistan province is relatively low. Given the impact of the disease stage on the survival rate, adequate access to appropriate diagnostic and treatment services as well as planning for screening and early diagnosis, especially in men, can increase the survival rate of patients. |
| first_indexed | 2024-12-21T14:45:19Z |
| format | Article |
| id | doaj.art-6e0fff804ade4d43a16b13325ba3c8d0 |
| institution | Directory Open Access Journal |
| issn | 1471-2490 |
| language | English |
| last_indexed | 2024-12-21T14:45:19Z |
| publishDate | 2020-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Urology |
| spelling | doaj.art-6e0fff804ade4d43a16b13325ba3c8d02022-12-21T19:00:03ZengBMCBMC Urology1471-24902020-12-012011910.1186/s12894-020-00769-1Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based studyMozhdeh Amiri0Sofimajidpour Heshmatollah1Nader Esmaeilnasab2Jamshid Khoubi3Ebrahim Ghaderi4Daem Roshani5Department of Epidemiology and Biostatistics, Faculty of Medicine, Kurdistan University of Medical SciencesDepartment of Urology, Faculty of Medicine, Kurdistan University of Medical SciencesSocial Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical SciencesEnvironmental Health Research Center, Research Institute for Health Development, Kurdistan University of Medical SciencesSocial Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical SciencesSocial Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical SciencesAbstract Background Bladder cancer is one of the most common urinary tract cancers. This study aims to estimate the survival rate of patients with bladder cancer according to the Cox proportional hazards model based on some key relevant variables. Methods In this retrospective population-based cohort study that explores the survival of patients with bladder cancer and its related factors, we first collected demographic information and medical records of 321 patients with bladder cancer through in-person and telephone interviews. Then, in the analysis phase, Kaplan–Meier method and log-rank test were used to draw the survival curve, compare the groups, and explore the effect of risk factors on the patient survival rate using Cox proportional hazards model. Results The median survival rate of patients was 63.2 (54.7–72) months and one, three and five-year survival rates were 87%, 68% and 54%, respectively. The results of multiple analyses using Cox's proportional hazards model revealed that variables of sex (male gender) (HR = 11.8, 95% CI: 0.4–100.7), more than 65 year of age (HR = 4.1, 95% CI: 0.4–11), occupation, income level, (HR = 0.4, 95% CI: 0.2–0.8), well differentiated tumor grade (HR = 3.2, 95% CI: 1.7–6) and disease stage influenced the survival rate of patients (p < 0.05). Conclusion The survival rate of patients with bladder cancer in Kurdistan province is relatively low. Given the impact of the disease stage on the survival rate, adequate access to appropriate diagnostic and treatment services as well as planning for screening and early diagnosis, especially in men, can increase the survival rate of patients.https://doi.org/10.1186/s12894-020-00769-1Survival rateBladder cancerPopulation basedCox proportional hazards model |
| spellingShingle | Mozhdeh Amiri Sofimajidpour Heshmatollah Nader Esmaeilnasab Jamshid Khoubi Ebrahim Ghaderi Daem Roshani Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study BMC Urology Survival rate Bladder cancer Population based Cox proportional hazards model |
| title | Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study |
| title_full | Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study |
| title_fullStr | Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study |
| title_full_unstemmed | Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study |
| title_short | Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study |
| title_sort | survival rate of patients with bladder cancer and its related factors in kurdistan province 2013 2018 a population based study |
| topic | Survival rate Bladder cancer Population based Cox proportional hazards model |
| url | https://doi.org/10.1186/s12894-020-00769-1 |
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