Biological Activities and Phytochemicals of Lungworts (Genus <i>Pulmonaria</i>) Focusing on <i>Pulmonaria</i> <i>officinalis</i>
Lungworts (members of genus <i>Pulmonaria</i>), especially <i>Pulmonaria officinalis</i>, have been used as medicinal plants in folk and traditional medicine. The potential biological activities of lungworts, such as antioxidant, anti-inflammatory, anti-neurodegenerative, ski...
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MDPI AG
2022-07-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/12/13/6678 |
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| author | Shweta Chauhan Varun Jaiswal Yeong-Im Cho Hae-Jeung Lee |
| author_facet | Shweta Chauhan Varun Jaiswal Yeong-Im Cho Hae-Jeung Lee |
| author_sort | Shweta Chauhan |
| collection | DOAJ |
| description | Lungworts (members of genus <i>Pulmonaria</i>), especially <i>Pulmonaria officinalis</i>, have been used as medicinal plants in folk and traditional medicine. The potential biological activities of lungworts, such as antioxidant, anti-inflammatory, anti-neurodegenerative, skin whitening, anticoagulant, antibacterial, anti-anemic, anticonvulsant, and wound-healing properties, have been observed in different studies. More than 90 phytochemicals belonging to pharmacologically active phytochemical classes have been reported for lungworts, which can be considered as one of the important contributors to the biological properties along with micronutrients. However, safety studies and clinical trials are missing for lungworts to establish most of their potential biological properties. Similarly, in vivo studies are lacking for anti-inflammatory and anti-neurodegenerative disorders and more in vivo studies are required to strengthen the knowledge of their antioxidant, anticoagulant, and anti-convulsant properties. A comprehensive compilation of the phytochemicals and biological properties of lungworts is also lacking in the literature, which can provide future direction for further pharmacological research. Hence, an attempt has been made in this study to compile the phytochemicals and biological properties to not only provide the resources for the design of further research to develop the pharmacological application of lungworts, but also to highlight the gaps and provide suggestions for future development. |
| first_indexed | 2024-03-09T22:06:34Z |
| format | Article |
| id | doaj.art-6e11851cb6e14e8fbecf1e14945464a1 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T22:06:34Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-6e11851cb6e14e8fbecf1e14945464a12023-11-23T19:40:56ZengMDPI AGApplied Sciences2076-34172022-07-011213667810.3390/app12136678Biological Activities and Phytochemicals of Lungworts (Genus <i>Pulmonaria</i>) Focusing on <i>Pulmonaria</i> <i>officinalis</i>Shweta Chauhan0Varun Jaiswal1Yeong-Im Cho2Hae-Jeung Lee3Department of Food and Nutrition, College of BioNano Technology, Gachon University, 1342 Seongnam-daero, Seongnam-si 13120, KoreaDepartment of Food and Nutrition, College of BioNano Technology, Gachon University, 1342 Seongnam-daero, Seongnam-si 13120, KoreaDepartment of Computer Engineering, College of IT, Gachon University, 1342 Seongnam-daero, Seongnam-si 13120, KoreaDepartment of Food and Nutrition, College of BioNano Technology, Gachon University, 1342 Seongnam-daero, Seongnam-si 13120, KoreaLungworts (members of genus <i>Pulmonaria</i>), especially <i>Pulmonaria officinalis</i>, have been used as medicinal plants in folk and traditional medicine. The potential biological activities of lungworts, such as antioxidant, anti-inflammatory, anti-neurodegenerative, skin whitening, anticoagulant, antibacterial, anti-anemic, anticonvulsant, and wound-healing properties, have been observed in different studies. More than 90 phytochemicals belonging to pharmacologically active phytochemical classes have been reported for lungworts, which can be considered as one of the important contributors to the biological properties along with micronutrients. However, safety studies and clinical trials are missing for lungworts to establish most of their potential biological properties. Similarly, in vivo studies are lacking for anti-inflammatory and anti-neurodegenerative disorders and more in vivo studies are required to strengthen the knowledge of their antioxidant, anticoagulant, and anti-convulsant properties. A comprehensive compilation of the phytochemicals and biological properties of lungworts is also lacking in the literature, which can provide future direction for further pharmacological research. Hence, an attempt has been made in this study to compile the phytochemicals and biological properties to not only provide the resources for the design of further research to develop the pharmacological application of lungworts, but also to highlight the gaps and provide suggestions for future development.https://www.mdpi.com/2076-3417/12/13/6678lungworts<i>Pulmonaria</i>antioxidantsbiological activityphytochemicals |
| spellingShingle | Shweta Chauhan Varun Jaiswal Yeong-Im Cho Hae-Jeung Lee Biological Activities and Phytochemicals of Lungworts (Genus <i>Pulmonaria</i>) Focusing on <i>Pulmonaria</i> <i>officinalis</i> Applied Sciences lungworts <i>Pulmonaria</i> antioxidants biological activity phytochemicals |
| title | Biological Activities and Phytochemicals of Lungworts (Genus <i>Pulmonaria</i>) Focusing on <i>Pulmonaria</i> <i>officinalis</i> |
| title_full | Biological Activities and Phytochemicals of Lungworts (Genus <i>Pulmonaria</i>) Focusing on <i>Pulmonaria</i> <i>officinalis</i> |
| title_fullStr | Biological Activities and Phytochemicals of Lungworts (Genus <i>Pulmonaria</i>) Focusing on <i>Pulmonaria</i> <i>officinalis</i> |
| title_full_unstemmed | Biological Activities and Phytochemicals of Lungworts (Genus <i>Pulmonaria</i>) Focusing on <i>Pulmonaria</i> <i>officinalis</i> |
| title_short | Biological Activities and Phytochemicals of Lungworts (Genus <i>Pulmonaria</i>) Focusing on <i>Pulmonaria</i> <i>officinalis</i> |
| title_sort | biological activities and phytochemicals of lungworts genus i pulmonaria i focusing on i pulmonaria i i officinalis i |
| topic | lungworts <i>Pulmonaria</i> antioxidants biological activity phytochemicals |
| url | https://www.mdpi.com/2076-3417/12/13/6678 |
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