Differential gene methylation and expression of HOX transcription factor family in orbitofacial neurofibroma

Differential gene methylation and expression of HOX transcription factor family in orbitofacial neurofibroma

Abstract Although most commonly benign, neurofibromas (NFs) can have devastating functional and cosmetic effects in addition to the possibility of malignant transformation. In orbitofacial neurofibromatosis type 1, NFs may cause progressive, disfiguring tumors of the lid, brow, temple, face and orbi...

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Bibliographic Details
Main Authors: Antje Arnold, Eddie Luidy Imada, Lisa Zhang, Deepak P. Edward, Luigi Marchionni, Fausto J. Rodriguez
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Acta Neuropathologica Communications
Subjects:
Neurofibromatosis
Orbitofacial
Neurofibromas
Plexiform neurofibromas
HOX genes
Online Access:http://link.springer.com/article/10.1186/s40478-020-00940-7

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