Fatal anaphylactic reaction during anesthesia
<p>Background: Incidence of anaphylactic reactions occuring during anesthesia is not known. They occur most often in the induction phase and can present with different levels of severity, also as an anaphylactic shock. Neuromuscular blocking drugs are the most frequently involved substa...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Slovenian Medical Association
2012-01-01
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| Series: | Zdravniški Vestnik |
| Online Access: | http://vestnik.szd.si/index.php/ZdravVest/article/view/827 |
| _version_ | 1830513693415178240 |
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| author | Izidor Kern Mihaela Zidarn Marko Bitenc |
| author_facet | Izidor Kern Mihaela Zidarn Marko Bitenc |
| author_sort | Izidor Kern |
| collection | DOAJ |
| description | <p>Background: Incidence of anaphylactic reactions occuring during anesthesia is not known. They occur most often in the induction phase and can present with different levels of severity, also as an anaphylactic shock. Neuromuscular blocking drugs are the most frequently involved substances.</p><p>Case presentation: We report a case of a 77-year old female patient with granulomatous inflammation of unknown etiology. Surgical biopsy of a neck lymph node was indicated. During the induction of anesthesia using propofol and succinylcholine she developed severe anaphylactic reaction presented with bronchospasm and cardiac arrest. Despite 80 min continous cardiopulmonary resuscitation the patient died. Elevated tryptase level in the patient’s blood sample taken before death confirmed anaphylactic reaction. On autopsy we confirmed the tuberculous etiology of generalized granulomatous inflammation.</p><p>Conclusions: It is important to recognize anaphylactic reaction during anesthesia early and to take adequate measures in order to prevent unfavorable outcome. Tryptase assay of a blood sample taken during life or postmortem may help to identify anaphylactic reaction.</p> |
| first_indexed | 2024-12-22T02:49:43Z |
| format | Article |
| id | doaj.art-6e12a6b5e71742309f6aea4ada29cd15 |
| institution | Directory Open Access Journal |
| issn | 1318-0347 1581-0224 |
| language | English |
| last_indexed | 2024-12-22T02:49:43Z |
| publishDate | 2012-01-01 |
| publisher | Slovenian Medical Association |
| record_format | Article |
| series | Zdravniški Vestnik |
| spelling | doaj.art-6e12a6b5e71742309f6aea4ada29cd152022-12-21T18:41:25ZengSlovenian Medical AssociationZdravniški Vestnik1318-03471581-02242012-01-01811706Fatal anaphylactic reaction during anesthesiaIzidor KernMihaela ZidarnMarko Bitenc<p>Background: Incidence of anaphylactic reactions occuring during anesthesia is not known. They occur most often in the induction phase and can present with different levels of severity, also as an anaphylactic shock. Neuromuscular blocking drugs are the most frequently involved substances.</p><p>Case presentation: We report a case of a 77-year old female patient with granulomatous inflammation of unknown etiology. Surgical biopsy of a neck lymph node was indicated. During the induction of anesthesia using propofol and succinylcholine she developed severe anaphylactic reaction presented with bronchospasm and cardiac arrest. Despite 80 min continous cardiopulmonary resuscitation the patient died. Elevated tryptase level in the patient’s blood sample taken before death confirmed anaphylactic reaction. On autopsy we confirmed the tuberculous etiology of generalized granulomatous inflammation.</p><p>Conclusions: It is important to recognize anaphylactic reaction during anesthesia early and to take adequate measures in order to prevent unfavorable outcome. Tryptase assay of a blood sample taken during life or postmortem may help to identify anaphylactic reaction.</p>http://vestnik.szd.si/index.php/ZdravVest/article/view/827 |
| spellingShingle | Izidor Kern Mihaela Zidarn Marko Bitenc Fatal anaphylactic reaction during anesthesia Zdravniški Vestnik |
| title | Fatal anaphylactic reaction during anesthesia |
| title_full | Fatal anaphylactic reaction during anesthesia |
| title_fullStr | Fatal anaphylactic reaction during anesthesia |
| title_full_unstemmed | Fatal anaphylactic reaction during anesthesia |
| title_short | Fatal anaphylactic reaction during anesthesia |
| title_sort | fatal anaphylactic reaction during anesthesia |
| url | http://vestnik.szd.si/index.php/ZdravVest/article/view/827 |
| work_keys_str_mv | AT izidorkern fatalanaphylacticreactionduringanesthesia AT mihaelazidarn fatalanaphylacticreactionduringanesthesia AT markobitenc fatalanaphylacticreactionduringanesthesia |