Spatial Transcriptomics Analysis Reveals that CCL17 and CCL22 are Robust Indicators of a Suppressive Immune Environment in Angioimmunoblastic T Cell Lymphoma (AITL)

Spatial Transcriptomics Analysis Reveals that CCL17 and CCL22 are Robust Indicators of a Suppressive Immune Environment in Angioimmunoblastic T Cell Lymphoma (AITL)

Background: T cell lymphoma is a complex and highly aggressive clinicopathological entity with a poor outcome. The angioimmunoblastic T-cell lymphoma (AITL) tumor immune microenvironment is poorly investigated. Methods: Here, to the best of our knowledge, spatial transcriptomics was applied for the...

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Bibliographic Details
Main Authors: Jun Du, Chen Qiu, Wei-Song Li, Bing Wang, Xin-Le Han, Su-Wen Lin, Xue-Hang Fu, Jian Hou, Zou-Fang Huang
Format: Article
Language:English
Published: IMR Press 2022-09-01
Series:Frontiers in Bioscience-Landmark
Subjects:
aitl
spatial transcriptomics
ccl17/ccl22-ccr4 axis
precision medicine
Online Access:https://www.imrpress.com/journal/FBL/27/9/10.31083/j.fbl2709270

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