Formulation and Characterization of Electrospun Nanofibers for Melatonin Ocular Delivery

Formulation and Characterization of Electrospun Nanofibers for Melatonin Ocular Delivery

The poor ocular bioavailability of melatonin (MEL) limits the therapeutic action the molecule could exert in the treatment of ocular diseases. To date, no study has explored the use of nanofiber-based inserts to prolong ocular surface contact time and improve MEL delivery. Here, the electrospinning...

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Bibliographic Details
Main Authors: Alessia Romeo, Adrienn Kazsoki, Safaa Omer, Balázs Pinke, László Mészáros, Teresa Musumeci, Romána Zelkó
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
nanofibers
ocular insert
electrospinning
PLA
PVA
in vitro dissolution study
Online Access:https://www.mdpi.com/1999-4923/15/4/1296

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