APOE4 Status and cognitive function in middle-aged and elderly people

APOE is one of the prominent genes involved in the increased risk of developing Alzheimer’s disease, but its effect on cognition in patients who are not yet diagnosed with dementia or mild cognitive impairment is relatively understudied. We aimed to examine the effect of ApoE4 on cognitive performan...

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Main Authors: Pavel N.A., Paun M.R., Matei P.V., Dutu I., Tudose C.
Format: Article
Language:English
Published: Sciendo 2023-03-01
Series:Balkan Journal of Medical Genetics
Subjects:
Online Access:https://doi.org/10.2478/bjmg-2022-0012
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author Pavel N.A.
Paun M.R.
Matei P.V.
Dutu I.
Tudose C.
author_facet Pavel N.A.
Paun M.R.
Matei P.V.
Dutu I.
Tudose C.
author_sort Pavel N.A.
collection DOAJ
description APOE is one of the prominent genes involved in the increased risk of developing Alzheimer’s disease, but its effect on cognition in patients who are not yet diagnosed with dementia or mild cognitive impairment is relatively understudied. We aimed to examine the effect of ApoE4 on cognitive performance in unimpaired middle-aged and elderly persons.
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spelling doaj.art-6e16577cec4946e58a8fc889d1e126882023-09-03T10:00:03ZengSciendoBalkan Journal of Medical Genetics1311-01602023-03-01251131810.2478/bjmg-2022-0012APOE4 Status and cognitive function in middle-aged and elderly peoplePavel N.A.0Paun M.R.1Matei P.V.2Dutu I.3Tudose C.4Psychiatry Department, University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania“Prof. Dr. Alexandru Obregia” Psychiatric Hospital, Bucharest, RomaniaPsychiatry Department, University of Medicine and Pharmacy “Carol Davila”, Bucharest, RomaniaPsychiatry Department, University of Medicine and Pharmacy “Carol Davila”, Bucharest, RomaniaPsychiatry Department, University of Medicine and Pharmacy “Carol Davila”, Bucharest, RomaniaAPOE is one of the prominent genes involved in the increased risk of developing Alzheimer’s disease, but its effect on cognition in patients who are not yet diagnosed with dementia or mild cognitive impairment is relatively understudied. We aimed to examine the effect of ApoE4 on cognitive performance in unimpaired middle-aged and elderly persons.https://doi.org/10.2478/bjmg-2022-0012apoecognitive impairmentelderlysubjective cognitive declinescd.
spellingShingle Pavel N.A.
Paun M.R.
Matei P.V.
Dutu I.
Tudose C.
APOE4 Status and cognitive function in middle-aged and elderly people
Balkan Journal of Medical Genetics
apoe
cognitive impairment
elderly
subjective cognitive decline
scd.
title APOE4 Status and cognitive function in middle-aged and elderly people
title_full APOE4 Status and cognitive function in middle-aged and elderly people
title_fullStr APOE4 Status and cognitive function in middle-aged and elderly people
title_full_unstemmed APOE4 Status and cognitive function in middle-aged and elderly people
title_short APOE4 Status and cognitive function in middle-aged and elderly people
title_sort apoe4 status and cognitive function in middle aged and elderly people
topic apoe
cognitive impairment
elderly
subjective cognitive decline
scd.
url https://doi.org/10.2478/bjmg-2022-0012
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AT mateipv apoe4statusandcognitivefunctioninmiddleagedandelderlypeople
AT dutui apoe4statusandcognitivefunctioninmiddleagedandelderlypeople
AT tudosec apoe4statusandcognitivefunctioninmiddleagedandelderlypeople