Cardiomyocyte electrical-mechanical synchronized model for high-content, dose-quantitative and time-dependent drug assessment
Abstract Cardiovascular diseases have emerged as a significant threat to human health. However, drug development is a time-consuming and costly process, and few drugs pass the preclinical assessment of safety and efficacy. The existing patch-clamp, Ca2+ imaging, and microelectrode array technologies...
Main Authors: | Jiaru Fang, Xinwei Wei, Hongbo Li, Ning Hu, Xingxing Liu, Dongxin Xu, Tao Zhang, Hao Wan, Ping Wang, Xi Xie |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Microsystems & Nanoengineering |
Online Access: | https://doi.org/10.1038/s41378-021-00247-0 |
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