Immunogenicity and protective efficacy of Ag85A and truncation of PstS1 fusion protein vaccines against tuberculosis

Immunogenicity and protective efficacy of Ag85A and truncation of PstS1 fusion protein vaccines against tuberculosis

Tuberculosis (TB) is an important public health problem, and the One Health approach is essential for controlling zoonotic tuberculosis. Therefore, a rationally designed and more effective TB vaccine is urgently needed. To enhance vaccine efficacy, it is important to design vaccine candidates that s...

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Bibliographic Details
Main Authors: Lingyuan Zeng, Xiuling Ma, Mengjin Qu, Minghui Tang, Huoming Li, Chengrui Lei, Jiahong Ji, Hao Li
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Tuberculosis
One health
Vaccine
Humoral immunity
Cellular immunity
Ag85A-tnPstS1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024030652

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