Handgrip Strength and Muscle Quality: Results from the National Health and Nutrition Examination Survey Database
Background: Handgrip strength (HGS) and the appendicular lean mass index (ALMI) are important determinants of sarcopenia. Muscle quality (MQ) is a measure of muscle strength relative to muscle mass. We examined trends in handgrip strength, the appendicular lean mass index, and analyzed their relatio...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-04-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/12/9/3184 |
| _version_ | 1797602306397569024 |
|---|---|
| author | Zhangxin Wen Jiaxuan Gu Rong Chen Qinyi Wang Na Ding Lingqiong Meng Xiangbing Wang Hong Liu Zhifeng Sheng Houfeng Zheng |
| author_facet | Zhangxin Wen Jiaxuan Gu Rong Chen Qinyi Wang Na Ding Lingqiong Meng Xiangbing Wang Hong Liu Zhifeng Sheng Houfeng Zheng |
| author_sort | Zhangxin Wen |
| collection | DOAJ |
| description | Background: Handgrip strength (HGS) and the appendicular lean mass index (ALMI) are important determinants of sarcopenia. Muscle quality (MQ) is a measure of muscle strength relative to muscle mass. We examined trends in handgrip strength, the appendicular lean mass index, and analyzed their relationship with age, anthropometry, and body composition in a sample of participants in the United States (US). Methods: This cross-sectional study analyzed data from 14,741 US males (49.7%) and females (50.3%) 6–80 years old who responded to the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2014. Dual X-ray absorptiometry was used to measure appendicular skeletal muscle mass. HGS was evaluated using the Takei Digital Grip Strength Dynamometer. Smoothed normative curves for HGS and the ALMI were constructed using a generalized additive model. Multiple regression analyses were used to examine associations of HGS and the ALMI with age, nutrition-related factors, physical activity, and body composition. Results: Mean HGS and the ALMI declined with advancing age. While mean HGS increased with the ALMI, it decreased with the fat mass index. HGS increased in males with an increase in body mass index, energy intake, the ALMI, and vitamins; however, HGS in females increased with albumin, but it had a negative association with the fat mass index and age, but not with increasing adiposity. Conclusions: HGS and the ALMI change with age: HGS increases with age, then stabilizes and declines; the ALMI increases with age, then stabilizes. In addition, we provide evidence for the effect of anthropometry, nutrition, physical activity, and body composition on HGS and the ALMI in US population. |
| first_indexed | 2024-03-11T04:15:14Z |
| format | Article |
| id | doaj.art-6e259473de0540059394d42319461064 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T04:15:14Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-6e259473de0540059394d423194610642023-11-17T23:11:49ZengMDPI AGJournal of Clinical Medicine2077-03832023-04-01129318410.3390/jcm12093184Handgrip Strength and Muscle Quality: Results from the National Health and Nutrition Examination Survey DatabaseZhangxin Wen0Jiaxuan Gu1Rong Chen2Qinyi Wang3Na Ding4Lingqiong Meng5Xiangbing Wang6Hong Liu7Zhifeng Sheng8Houfeng Zheng9Department of Metabolism and Endocrinology, Zhuzhou Hospital of Xiangya School of Medicine, Central South University, 116 Changjiang South Road, Zhuzhou 412007, ChinaDiseases & Population (DaP) Geninfo Lab, School of Lifesciences, Westlake University, 600 Dunyu Road, Hangzhou 310030, ChinaKey Laboratory of Endocrinology, Department of Endocrinology, National Health and Family Planning Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Shuaifuyuan No. 1, Beijing 100730, ChinaNational Clinical Research Center for Metabolic Diseases, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, Department of Metabolism and Endocrinology, Health Management Center, The Second Xiangya Hospital of Central South University, 139 Middle Renmin Road, Changsha 410011, ChinaDepartment of Metabolism and Endocrinology, Zhuzhou Hospital of Xiangya School of Medicine, Central South University, 116 Changjiang South Road, Zhuzhou 412007, ChinaDepartment of Nutritional Sciences, Rutgers University, New Brunswick, NJ 08901, USADivisions of Endocrinology, Metabolism and Nutrition, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USADepartment of Metabolism and Endocrinology, Zhuzhou Hospital of Xiangya School of Medicine, Central South University, 116 Changjiang South Road, Zhuzhou 412007, ChinaNational Clinical Research Center for Metabolic Diseases, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, Department of Metabolism and Endocrinology, Health Management Center, The Second Xiangya Hospital of Central South University, 139 Middle Renmin Road, Changsha 410011, ChinaDiseases & Population (DaP) Geninfo Lab, School of Lifesciences, Westlake University, 600 Dunyu Road, Hangzhou 310030, ChinaBackground: Handgrip strength (HGS) and the appendicular lean mass index (ALMI) are important determinants of sarcopenia. Muscle quality (MQ) is a measure of muscle strength relative to muscle mass. We examined trends in handgrip strength, the appendicular lean mass index, and analyzed their relationship with age, anthropometry, and body composition in a sample of participants in the United States (US). Methods: This cross-sectional study analyzed data from 14,741 US males (49.7%) and females (50.3%) 6–80 years old who responded to the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2014. Dual X-ray absorptiometry was used to measure appendicular skeletal muscle mass. HGS was evaluated using the Takei Digital Grip Strength Dynamometer. Smoothed normative curves for HGS and the ALMI were constructed using a generalized additive model. Multiple regression analyses were used to examine associations of HGS and the ALMI with age, nutrition-related factors, physical activity, and body composition. Results: Mean HGS and the ALMI declined with advancing age. While mean HGS increased with the ALMI, it decreased with the fat mass index. HGS increased in males with an increase in body mass index, energy intake, the ALMI, and vitamins; however, HGS in females increased with albumin, but it had a negative association with the fat mass index and age, but not with increasing adiposity. Conclusions: HGS and the ALMI change with age: HGS increases with age, then stabilizes and declines; the ALMI increases with age, then stabilizes. In addition, we provide evidence for the effect of anthropometry, nutrition, physical activity, and body composition on HGS and the ALMI in US population.https://www.mdpi.com/2077-0383/12/9/3184sarcopeniahandgrip strengthappendicular lean mass indexagephysical activity |
| spellingShingle | Zhangxin Wen Jiaxuan Gu Rong Chen Qinyi Wang Na Ding Lingqiong Meng Xiangbing Wang Hong Liu Zhifeng Sheng Houfeng Zheng Handgrip Strength and Muscle Quality: Results from the National Health and Nutrition Examination Survey Database Journal of Clinical Medicine sarcopenia handgrip strength appendicular lean mass index age physical activity |
| title | Handgrip Strength and Muscle Quality: Results from the National Health and Nutrition Examination Survey Database |
| title_full | Handgrip Strength and Muscle Quality: Results from the National Health and Nutrition Examination Survey Database |
| title_fullStr | Handgrip Strength and Muscle Quality: Results from the National Health and Nutrition Examination Survey Database |
| title_full_unstemmed | Handgrip Strength and Muscle Quality: Results from the National Health and Nutrition Examination Survey Database |
| title_short | Handgrip Strength and Muscle Quality: Results from the National Health and Nutrition Examination Survey Database |
| title_sort | handgrip strength and muscle quality results from the national health and nutrition examination survey database |
| topic | sarcopenia handgrip strength appendicular lean mass index age physical activity |
| url | https://www.mdpi.com/2077-0383/12/9/3184 |
| work_keys_str_mv | AT zhangxinwen handgripstrengthandmusclequalityresultsfromthenationalhealthandnutritionexaminationsurveydatabase AT jiaxuangu handgripstrengthandmusclequalityresultsfromthenationalhealthandnutritionexaminationsurveydatabase AT rongchen handgripstrengthandmusclequalityresultsfromthenationalhealthandnutritionexaminationsurveydatabase AT qinyiwang handgripstrengthandmusclequalityresultsfromthenationalhealthandnutritionexaminationsurveydatabase AT nading handgripstrengthandmusclequalityresultsfromthenationalhealthandnutritionexaminationsurveydatabase AT lingqiongmeng handgripstrengthandmusclequalityresultsfromthenationalhealthandnutritionexaminationsurveydatabase AT xiangbingwang handgripstrengthandmusclequalityresultsfromthenationalhealthandnutritionexaminationsurveydatabase AT hongliu handgripstrengthandmusclequalityresultsfromthenationalhealthandnutritionexaminationsurveydatabase AT zhifengsheng handgripstrengthandmusclequalityresultsfromthenationalhealthandnutritionexaminationsurveydatabase AT houfengzheng handgripstrengthandmusclequalityresultsfromthenationalhealthandnutritionexaminationsurveydatabase |