Toxoplasma gondii alters NMDAR signaling and induces signs of Alzheimer’s disease in wild-type, C57BL/6 mice

Toxoplasma gondii alters NMDAR signaling and induces signs of Alzheimer’s disease in wild-type, C57BL/6 mice

Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disease associated with cognitive decline and complete loss of basic functions. The ubiquitous apicomplexan parasite Toxoplasma gondii (T. gondii) infects up to one third of the world’s population and is implicated in AD...

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Bibliographic Details
Main Authors: Luisa Torres, Sudie-Ann Robinson, Do-Geun Kim, Angela Yan, Thomas A. Cleland, Margaret S. Bynoe
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Neuroinflammation
Subjects:
Alzheimer’s disease
Toxoplasma gondii
NMDAR
Amyloid beta
Olfactory sensory neurons
Online Access:http://link.springer.com/article/10.1186/s12974-018-1086-8

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