Meta-analysis of cryoablation versus radiofrequency ablation in the treatment of malignant liver tumors
AbstractObjective A meta-analysis was conducted to assess the efficacy and safety of cryoablation (CRA) compared with radiofrequency ablation (RFA).Methods A systematic search of PubMed, EMBASE, Cochrane Library, Wanfang, CNKI, and VIP databases was conducted to identify clinical controlled studies...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2023.2300347 |
| _version_ | 1797361509867716608 |
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| author | Xiangzhong Huang Xinjian Xu Hongtao Du Qiulian Sun Minyu Wu |
| author_facet | Xiangzhong Huang Xinjian Xu Hongtao Du Qiulian Sun Minyu Wu |
| author_sort | Xiangzhong Huang |
| collection | DOAJ |
| description | AbstractObjective A meta-analysis was conducted to assess the efficacy and safety of cryoablation (CRA) compared with radiofrequency ablation (RFA).Methods A systematic search of PubMed, EMBASE, Cochrane Library, Wanfang, CNKI, and VIP databases was conducted to identify clinical controlled studies comparing CRA versus RFA for hepatic malignancies up to July 2022. The meta-analysis was performed using RevMan 5.3.Results A comprehensive analysis was conducted on 8 clinical controlled studies involving a total of 943 patients. There were no significant differences in the incidence of complications, complete ablation of lesions, local recurrence, and 1-year survival between the CRA and RFA groups (OR = 0.98, 95%CI: 0.61–1.55, p = 0.92; OR = 1.08, 95%CI: 0.62–1.90, p = 0.78; OR = 1.28, 95%CI: 0.49–3.36, p = 0.61; and OR = 1.14, 95%CI: 0.63–2.06, p = 0.66, respectively).Conclusion The efficacy and safety profile of CRA was comparable to that of RFA in the context of ablation therapy for hepatic malignancies. These findings suggested that CRA may be a valuable alternative to RFA in the treatment of hepatic malignancies. |
| first_indexed | 2024-03-08T15:54:42Z |
| format | Article |
| id | doaj.art-6e29dfd506e8462ab18281d12e3e2964 |
| institution | Directory Open Access Journal |
| issn | 0265-6736 1464-5157 |
| language | English |
| last_indexed | 2024-03-08T15:54:42Z |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj.art-6e29dfd506e8462ab18281d12e3e29642024-01-08T22:38:16ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572024-12-0141110.1080/02656736.2023.2300347Meta-analysis of cryoablation versus radiofrequency ablation in the treatment of malignant liver tumorsXiangzhong Huang0Xinjian Xu1Hongtao Du2Qiulian Sun3Minyu Wu4Department of Interventional Radiology, Jiangyin Hospital Affiliated to Nantong University, Jiangyin City, Jiangsu Province, ChinaDepartment of Interventional Radiology, Jiangyin Hospital Affiliated to Nantong University, Jiangyin City, Jiangsu Province, ChinaDepartment of Radiology, Xuzhou Central Hospital, Xuzhou City, Jiangsu Province, ChinaDepartment of Radiology, The Fifth People’s Hospital of Suzhou, Suzhou City, Jiangsu Province, ChinaDepartment of Radiology, The Fifth People’s Hospital of Suzhou, Suzhou City, Jiangsu Province, ChinaAbstractObjective A meta-analysis was conducted to assess the efficacy and safety of cryoablation (CRA) compared with radiofrequency ablation (RFA).Methods A systematic search of PubMed, EMBASE, Cochrane Library, Wanfang, CNKI, and VIP databases was conducted to identify clinical controlled studies comparing CRA versus RFA for hepatic malignancies up to July 2022. The meta-analysis was performed using RevMan 5.3.Results A comprehensive analysis was conducted on 8 clinical controlled studies involving a total of 943 patients. There were no significant differences in the incidence of complications, complete ablation of lesions, local recurrence, and 1-year survival between the CRA and RFA groups (OR = 0.98, 95%CI: 0.61–1.55, p = 0.92; OR = 1.08, 95%CI: 0.62–1.90, p = 0.78; OR = 1.28, 95%CI: 0.49–3.36, p = 0.61; and OR = 1.14, 95%CI: 0.63–2.06, p = 0.66, respectively).Conclusion The efficacy and safety profile of CRA was comparable to that of RFA in the context of ablation therapy for hepatic malignancies. These findings suggested that CRA may be a valuable alternative to RFA in the treatment of hepatic malignancies.https://www.tandfonline.com/doi/10.1080/02656736.2023.2300347Malignant liver tumorcryoablationradiofrequency ablationmeta-analysis |
| spellingShingle | Xiangzhong Huang Xinjian Xu Hongtao Du Qiulian Sun Minyu Wu Meta-analysis of cryoablation versus radiofrequency ablation in the treatment of malignant liver tumors International Journal of Hyperthermia Malignant liver tumor cryoablation radiofrequency ablation meta-analysis |
| title | Meta-analysis of cryoablation versus radiofrequency ablation in the treatment of malignant liver tumors |
| title_full | Meta-analysis of cryoablation versus radiofrequency ablation in the treatment of malignant liver tumors |
| title_fullStr | Meta-analysis of cryoablation versus radiofrequency ablation in the treatment of malignant liver tumors |
| title_full_unstemmed | Meta-analysis of cryoablation versus radiofrequency ablation in the treatment of malignant liver tumors |
| title_short | Meta-analysis of cryoablation versus radiofrequency ablation in the treatment of malignant liver tumors |
| title_sort | meta analysis of cryoablation versus radiofrequency ablation in the treatment of malignant liver tumors |
| topic | Malignant liver tumor cryoablation radiofrequency ablation meta-analysis |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2023.2300347 |
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