miR-146a Overexpression in Oral Squamous Cell Carcinoma Potentiates Cancer Cell Migration and Invasion Possibly via Targeting HTT

miR-146a Overexpression in Oral Squamous Cell Carcinoma Potentiates Cancer Cell Migration and Invasion Possibly via Targeting HTT

Huntingtin (HTT) is one of the target genes of miR-146-a and regulates various cancer cell activities. This study aims to explore the miR-146a expression pattern in oral squamous cell carcinoma (OSCC) and its role and mechanism in OSCC progression and metastasis via targeting the HTT gene. OSCC tiss...

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Bibliographic Details
Main Authors: Liping Wang, Yunxin Chen, Yongyong Yan, Xueqi Guo, Ying Fang, Yucheng Su, Lijing Wang, Janak L. Pathak, Linhu Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
oral squamous cell carcinoma
mir-146a
Huntington gene
migration
invasion
metastasis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.585976/full

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