Evaluation of Central Macula, Retinal Nerve Fiber Layer, and Ganglion Cell Complex Thickness in Congenital Color Vision Deficiency
INTRODUCTION[|]This study was designed to evaluate the thickness of the central macula, the retinal nerve fiber layer (RNFL), and the ganglion cell complex (GCC) in individuals with congenital red-green color vision deficiency (CVD) using spectral-domain optical coherence tomography (SD-OCT).[¤]METH...
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| Format: | Article |
| Language: | English |
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KARE Publishing
2020-08-01
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| Series: | Beyoglu Eye Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-83703 |
| _version_ | 1797922527058591744 |
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| author | Ercan Ozsoy Fatih Celik Nagehan Can Elif Yusufoglu Dogukan Comerter |
| author_facet | Ercan Ozsoy Fatih Celik Nagehan Can Elif Yusufoglu Dogukan Comerter |
| author_sort | Ercan Ozsoy |
| collection | DOAJ |
| description | INTRODUCTION[|]This study was designed to evaluate the thickness of the central macula, the retinal nerve fiber layer (RNFL), and the ganglion cell complex (GCC) in individuals with congenital red-green color vision deficiency (CVD) using spectral-domain optical coherence tomography (SD-OCT).[¤]METHODS[|]This study included 22 males with a red-green CVD (Group 1) and 22 males with normal color vision (Group 2). The Ishihara test was used to determine CVD. SD-OCT was used to evaluate the central macula, RNFL, and GCC measurements of all of the study participants. The quantitative data of the 2 groups were compared. The Kruskal-Wallis test was used for the statistical analysis and a p value <0.05 was considered significant.[¤]RESULTS[|]The mean central macula thickness observed in Group 1 and 2 was 255.00+-25.50 μm and 248.95+-24.70 μm, respectively. The mean RNFL thickness of Group 1 and 2 was 110.66+-14.70 μm and 109.49+-9.90 μm, respectively, and the mean GCC thickness of Group 1 and 2 was 97.70+-10.80 μm and 97.56+-5.10 μm, respectively. There were no significant differences between the groups in the assessment of the central macula, RNFL, or GCC thickness (p=0.20, p=0.34, p=0.37).[¤]DISCUSSION AND CONCLUSION[|]The results of this study suggested that congenital red-green CVD does not affect the thickness of the central macula, RNFL, or GCC. To the best of our knowledge, this is the first study to evaluate the thickness of the GCC in individuals with congenital red-green CVD.[¤] |
| first_indexed | 2024-04-10T14:33:46Z |
| format | Article |
| id | doaj.art-6e2aaa28040d499da535cc1f3bae7ac7 |
| institution | Directory Open Access Journal |
| issn | 2587-0394 |
| language | English |
| last_indexed | 2024-04-10T14:33:46Z |
| publishDate | 2020-08-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Beyoglu Eye Journal |
| spelling | doaj.art-6e2aaa28040d499da535cc1f3bae7ac72023-02-15T16:08:41ZengKARE PublishingBeyoglu Eye Journal2587-03942020-08-0152818510.14744/bej.2020.83703BEJ-83703Evaluation of Central Macula, Retinal Nerve Fiber Layer, and Ganglion Cell Complex Thickness in Congenital Color Vision DeficiencyErcan Ozsoy0Fatih Celik1Nagehan Can2Elif Yusufoglu3Dogukan Comerter4Department of Ophthalmology, University of Health Sciences, Haseki Training and Research Hospital, Istanbul, TurkeyDepartment of Ophthalmology, University of Health Sciences, Elazıg Fethi Sekin City Hospital, Elazıg, TurkeyDepartment of Ophthalmology, Torbali State Hospital, Izmir, TurkeyDepartment of Ophthalmology, University of Health Sciences, Elazıg Fethi Sekin City Hospital, Elazıg, TurkeyDepartment of Ophthalmology, University of Health Sciences, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, TurkeyINTRODUCTION[|]This study was designed to evaluate the thickness of the central macula, the retinal nerve fiber layer (RNFL), and the ganglion cell complex (GCC) in individuals with congenital red-green color vision deficiency (CVD) using spectral-domain optical coherence tomography (SD-OCT).[¤]METHODS[|]This study included 22 males with a red-green CVD (Group 1) and 22 males with normal color vision (Group 2). The Ishihara test was used to determine CVD. SD-OCT was used to evaluate the central macula, RNFL, and GCC measurements of all of the study participants. The quantitative data of the 2 groups were compared. The Kruskal-Wallis test was used for the statistical analysis and a p value <0.05 was considered significant.[¤]RESULTS[|]The mean central macula thickness observed in Group 1 and 2 was 255.00+-25.50 μm and 248.95+-24.70 μm, respectively. The mean RNFL thickness of Group 1 and 2 was 110.66+-14.70 μm and 109.49+-9.90 μm, respectively, and the mean GCC thickness of Group 1 and 2 was 97.70+-10.80 μm and 97.56+-5.10 μm, respectively. There were no significant differences between the groups in the assessment of the central macula, RNFL, or GCC thickness (p=0.20, p=0.34, p=0.37).[¤]DISCUSSION AND CONCLUSION[|]The results of this study suggested that congenital red-green CVD does not affect the thickness of the central macula, RNFL, or GCC. To the best of our knowledge, this is the first study to evaluate the thickness of the GCC in individuals with congenital red-green CVD.[¤]https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-83703colorganglionnervered-greenthickness. |
| spellingShingle | Ercan Ozsoy Fatih Celik Nagehan Can Elif Yusufoglu Dogukan Comerter Evaluation of Central Macula, Retinal Nerve Fiber Layer, and Ganglion Cell Complex Thickness in Congenital Color Vision Deficiency Beyoglu Eye Journal color ganglion nerve red-green thickness. |
| title | Evaluation of Central Macula, Retinal Nerve Fiber Layer, and Ganglion Cell Complex Thickness in Congenital Color Vision Deficiency |
| title_full | Evaluation of Central Macula, Retinal Nerve Fiber Layer, and Ganglion Cell Complex Thickness in Congenital Color Vision Deficiency |
| title_fullStr | Evaluation of Central Macula, Retinal Nerve Fiber Layer, and Ganglion Cell Complex Thickness in Congenital Color Vision Deficiency |
| title_full_unstemmed | Evaluation of Central Macula, Retinal Nerve Fiber Layer, and Ganglion Cell Complex Thickness in Congenital Color Vision Deficiency |
| title_short | Evaluation of Central Macula, Retinal Nerve Fiber Layer, and Ganglion Cell Complex Thickness in Congenital Color Vision Deficiency |
| title_sort | evaluation of central macula retinal nerve fiber layer and ganglion cell complex thickness in congenital color vision deficiency |
| topic | color ganglion nerve red-green thickness. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-83703 |
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